CAS 147794-23-8|ω-Conotoxin MVIIC

Introduction：Basic information about CAS 147794-23-8|ω-Conotoxin MVIIC, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. ω-Conotoxin MVIIC BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles28
6. Synonyms

Common Name	ω-Conotoxin MVIIC
CAS Number	147794-23-8	Molecular Weight	2749.251
Density	1.6±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₁₀₆H₁₇₈N₄₀O₃₂S₇	Melting Point	/
MSDS	USA	Flash Point	/

Names

Name	{(1R,4S,7S,10S,13S,16S,19S,22R,27R,30S,36S,39S,45R,48S,54S,57R,62R,65S,71S,77S,83S)-62-Amino-7,30,65,71-tetrakis(4-aminobutyl)-4,36,39-tris(3-carbamimidamidopropyl)-27-carbamoyl-16-(4-hydroxybenzyl)-10-(1-hydroxyethyl)-48,54-bis(hydroxymethyl)-77-methyl-13-[2-(methylsulfanyl)ethyl]-2,5,8,11,14,17,20,29,32,35,38,41,44,47,50,53,56,63,66,69,72,75,78,84,91-pentacosaoxo-24,25,59,60,87,88-hexathia-3,6,9,12,15,18,21,28,31,34,37,40,43,46,49,52,55,6$CYS-LYS-GLY-LYS-GLY-ALA-PRO-CYS-ARG-LYS-THR-MET-TYR-ASP-CYS-CYS-SER-GLY-SER-CYS-GLY-ARG-ARG-GLY-LYS-CYS-NH2
Synonym	More Synonyms

Name

{(1R,4S,7S,10S,13S,16S,19S,22R,27R,30S,36S,39S,45R,48S,54S,57R,62R,65S,71S,77S,83S)-62-Amino-7,30,65,71-tetrakis(4-aminobutyl)-4,36,39-tris(3-carbamimidamidopropyl)-27-carbamoyl-16-(4-hydroxybenzyl)-10-(1-hydroxyethyl)-48,54-bis(hydroxymethyl)-77-methyl-13-[2-(methylsulfanyl)ethyl]-2,5,8,11,14,17,20,29,32,35,38,41,44,47,50,53,56,63,66,69,72,75,78,84,91-pentacosaoxo-24,25,59,60,87,88-hexathia-3,6,9,12,15,18,21,28,31,34,37,40,43,46,49,52,55,6$CYS-LYS-GLY-LYS-GLY-ALA-PRO-CYS-ARG-LYS-THR-MET-TYR-ASP-CYS-CYS-SER-GLY-SER-CYS-GLY-ARG-ARG-GLY-LYS-CYS-NH2

Synonym

More Synonyms

ω-Conotoxin MVIIC BiologicalActivity

Description	ω-Conotoxin MVIIC is a N- and P/Q-type Ca2+ channel blocker, significantly suppresses the 11-keto-βboswellic acid-mediated inhibition of glutamate release[1].
Related Catalog	Signaling Pathways >>Membrane Transporter/Ion Channel >>Calcium ChannelResearch Areas >>Neurological Disease
References	[1]. Cheng Wei Lu, et al. 11-Keto-β-Boswellic Acid Attenuates Glutamate Release and Kainic Acid-Induced Excitotoxicity in the Rat Hippocampus. Planta Med. 2020 Apr;86(6):434-441.

Chemical & Physical Properties

Density	1.6±0.1 g/cm3
Molecular Formula	C₁₀₆H₁₇₈N₄₀O₃₂S₇
Molecular Weight	2749.251
Exact Mass	2747.157471
PSA	1372.92000
LogP	-20.33
Index of Refraction	1.723
InChIKey	FHVUTHWUIUXZBY-CJZHFHNWSA-N
SMILES	CSCCC1NC(=O)C(C(C)O)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C2CSSCC3NC(=O)C(CO)NC(=O)CNC(=O)C(CO)NC(=O)C(CSSCC(N)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCCN)C(=O)NCC(=O)NC(C)C(=O)N4CCCC4C(=O)N2)NC(=O)C(CSSCC(C(N)=O)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)CNC3=O)NC(=O)C(CC(=O)O)NC(=O)C(Cc2ccc(O)cc2)NC1=O

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	UN 3172
Packaging Group	III
Hazard Class	6.1(b)

Articles28

Mechanisms underlying mechanosensitivity of mesenteric afferent fibers to vascular flow.

Am. J. Physiol. Gastrointest. Liver Physiol. 293(2) , G422-8, (2007)

Spinal afferent neurons, with endings in the intestinal mesenteries, have been shown to respond to changes in vascular perfusion rates. The mechanisms underlying this sensitivity were investigated in ...

Glutamate regulates neurite outgrowth of cultured descending brain neurons from larval lamprey.

Dev. Neurobiol. 67(2) , 173-88, (2007)

In larval lamprey, descending brain neurons, which regenerate their axons following spinal cord injury, were isolated and examined in cell culture to identify some of the factors that regulate neurite...

Effects of Ca2+ channel antagonists on acetylcholine and catecholamine releases in the in vivo rat adrenal medulla.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 287(1) , R161-6, (2004)

To elucidate the types of voltage-dependent Ca(2+) channels controlling ACh and catecholamine releases in the in vivo adrenal medulla, we implanted microdialysis probes in the left adrenal medulla of ...

Synonyms

CTX MVIIC

conotoxin MVIIC

omega-Conotoxin M VIIC

Snx 230

conotoxin MVIIC_smartox

{(1R,4S,7S,13S,16S,19S,22R,27R,30S,36S,39S,45R,48S,54S,57R,62R,65S,71S,77S,83S)-62-Amino-7,30,65,71-tetrakis(4-aminobutyl)-4,36,39-tris(3-carbamimidamidopropyl)-27-carbamoyl-16-(4-hydroxybenzyl)-10-[(1R)-1-hydroxyethyl]-48,54-bis(hydroxymethyl)-77-methyl-13-[2-(methylsulfanyl)ethyl]-2,5,8,11,14,17,20,29,32,35,38,41,44,47,50,53,56,63,66,69,72,75,78,84,91-pentacosaoxo-24,25,59,60,87,88-hexathia-3,6,9,12,15,18,21,28,31,34,37,40,43,46,49,52,55,

Recommended......