CAS 146724-94-9|DETA-NONOate

Introduction:Basic information about CAS 146724-94-9|DETA-NONOate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameDETA-NONOate
CAS Number146724-94-9Molecular Weight163.178
Density1.5±0.1 g/cm3Boiling Point303.0±52.0 °C at 760 mmHg
Molecular FormulaC4H13N5O2Melting Point98-106ºC
MSDSUSAFlash Point137.1±30.7 °C

Names

Name1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane
SynonymMore Synonyms

DETA-NONOate BiologicalActivity

DescriptionNOC 18 is a nitric oxide donor and activates an inward current in cultured rat cerebellar granules cells. NOC 18 increases cGMP production in cultured vascular smooth muscle cells. NOC 18 reduces contractility of cardiac muscle preparations in vitro.
Related CatalogSignaling Pathways >>Immunology/Inflammation >>NO Synthase

Chemical & Physical Properties

Density1.5±0.1 g/cm3
Boiling Point303.0±52.0 °C at 760 mmHg
Melting Point98-106ºC
Molecular FormulaC4H13N5O2
Molecular Weight163.178
Flash Point137.1±30.7 °C
Exact Mass163.106918
PSA108.18000
LogP-1.65
Vapour Pressure0.0±1.4 mmHg at 25°C
Index of Refraction1.588
InChIKeyYNRCBOXEDICOIX-VQHVLOKHSA-N
SMILESNCCN(CCN)[N+]([O-])=NO
Storage condition−20°C
Water SolubilityH2O: >20 mg/mL

Safety Information

Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi
Risk PhrasesR36/37/38
Safety Phrases26-36
RIDADRNONH for all modes of transport
WGK Germany3
RTECSKH2502500
HS Code2928000090

Customs

HS Code2928000090
Summary2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles57

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In vivo imaging of reactive oxygen species in mouse brain by using [3H]hydromethidine as a potential radical trapping radiotracer.

J. Cereb. Blood Flow Metab. 34(12) , 1907-13, (2014)

To assess reactive oxygen species (ROS) production by detecting the fluorescent oxidation product, hydroethidine has been used extensively. The present study was undertaken to evaluate the potential o...

Regulation of microglial migration, phagocytosis, and neurite outgrowth by HO-1/CO signaling.

Dev. Neurobiol. 75 , 854-76, (2015)

Clearance of infected and apoptotic neuronal corpses during inflammatory conditions is a fundamental process to create a favorable environment for neuronal recovery. Microglia are the resident immune ...

Preservation of nitric oxide-induced relaxation of porcine coronary artery: roles of the dimers of soluble guanylyl cyclase, phosphodiesterase type 5, and cGMP-dependent protein kinase.

Pflugers Arch. 466(10) , 1999-2008, (2014)

Soluble guanylyl cyclase (sGC), phosphodiesterase type 5 (PDE5), and guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase (PKG) are all dimeric. The present study was to determine the ...

Synonyms

1,1-Bis(2-aminoethyl)-2-hydroxy-3-oxotriazane
3,3-Bis(aminoethyl)-1-hydroxy-2-oxo-1-triazene
N-[bis(2-aminoethyl)amino]-N-hydroxynitrous amide
MFCD00278808
Diethylenetriamine nitric oxide adduct
DETA NONOate
2,2'-(hydroxynitrosohydrazono)bis-ethanamine
Ethanamine, 2,2'-(2-hydroxy-3-oxotriazanylidene)bis-
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