CAS 5725-91-7|7-Ethoxyresorufin
| Common Name | 7-Ethoxyresorufin | ||
|---|---|---|---|
| CAS Number | 5725-91-7 | Molecular Weight | 241.242 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 389.3±42.0 °C at 760 mmHg |
| Molecular Formula | C14H11NO3 | Melting Point | 223-225ºC(lit.) |
| MSDS | ChineseUSA | Flash Point | 185.9±22.3 °C |
Names
| Name | 7-ethoxyresorufin |
|---|---|
| Synonym | More Synonyms |
7-Ethoxyresorufin BiologicalActivity
| Description | 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Cytochrome P450Research Areas >>OthersSignaling Pathways >>Immunology/Inflammation >>NO Synthase |
| References | [1]. C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450. Br J Pharmacol. 1996 May;118(1):57-62. [2]. Thomas K H Chang, et al. Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. Methods Mol Biol. 2006;320:85-90. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 389.3±42.0 °C at 760 mmHg |
| Melting Point | 223-225ºC(lit.) |
| Molecular Formula | C14H11NO3 |
| Molecular Weight | 241.242 |
| Flash Point | 185.9±22.3 °C |
| Exact Mass | 241.073898 |
| PSA | 52.33000 |
| LogP | 2.02 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.624 |
| InChIKey | CRCWUBLTFGOMDD-UHFFFAOYSA-N |
| SMILES | CCOc1ccc2nc3ccc(=O)cc-3oc2c1 |
| Storage condition | -20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Synonyms
| resorufin, 7-ethoxy- |
| 7-Ethoxy-3H-phenoxazin-3-one |
| MFCD00037661 |
| 7-Ethoxyresorufin |
| 7-Ethoxy Resorufin |
| 7-ethoxyphenoxazin-3-one |
| Resorufin ethyl ether |
| 3H-Phenoxazin-3-one, 7-ethoxy- |
