CAS 15883-20-2|N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide

Introduction：Basic information about CAS 15883-20-2|N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles25
7. Synonyms

Common Name	N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide
CAS Number	15883-20-2	Molecular Weight	232.321
Density	1.1±0.1 g/cm3	Boiling Point	392.3±42.0 °C at 760 mmHg
Molecular Formula	C₁₄H₂₀N₂O	Melting Point	114-117ºC
MSDS	ChineseUSA	Flash Point	149.0±28.0 °C
Symbol	GHS06	Signal Word	Danger

Names

Name	N-(2,6-Dimethylphenl)-2-Piperidine Carboxamide
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	392.3±42.0 °C at 760 mmHg
Melting Point	114-117ºC
Molecular Formula	C₁₄H₂₀N₂O
Molecular Weight	232.321
Flash Point	149.0±28.0 °C
Exact Mass	232.157562
PSA	41.13000
LogP	2.29
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.567
InChIKey	SILRCGDPZGQJOQ-UHFFFAOYSA-N
SMILES	Cc1cccc(C)c1NC(=O)C1CCCCN1
Storage condition	-20°C Freezer

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM6076000

CHEMICAL NAME :: 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-

CAS REGISTRY NUMBER :: 15883-20-2

BEILSTEIN REFERENCE NO. :: 0206391

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C14-H20-N2-O

MOLECULAR WEIGHT :: 232.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CEXPB9 Clinical and Experimental Pharmacology and Physiology. (Blackwell Scientific Publications, (Australia) Pty Ltd., 107 Barry St., Carlton, Vic. 3053, Australia) V.1- 1974- Volume(issue)/page/year: 21,997,1994

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0155176

Safety Information

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301
Precautionary Statements	Missing Phrase - N15.00950417
Hazard Codes	Xi: Irritant;
Risk Phrases	25
Safety Phrases	45
RIDADR	UN 2811 6.1 / PGIII
RTECS	TM6076000
HS Code	2933399090

Customs

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles25

Kinetics of bupivacaine after clonidine pretreatment in mice.

Can. J. Anaesth. 42(5 Pt 1) , 434-7, (1995)

Previous studies have reported that clonidine pretreatment causes an increase in the local anaesthetic activity of bupivacaine. This study was designed to document possible changes in the pharmacokine...

Population pharmacokinetic analysis of ropivacaine and its metabolite 2',6'-pipecoloxylidide from pooled data in neonates, infants, and children.

Br. J. Anaesth. 107(3) , 409-24, (2011)

The aim was to characterize ropivacaine and 2',6'-pipecoloxylidide (PPX) pharmacokinetics and factors affecting them in paediatric anaesthesia.Population pharmacokinetics of ropivacaine and its active...

Bupivacaine kinetics during hyperthermia in rats.

Can. J. Anaesth. 41(3) , 253-6, (1994)

The aim of this study was to document possible alterations of bupivacaine pharmacokinetic behaviour in rats during hyperthermia. Two groups of Wistar AF IO PS male rats (Group A = normothermic control...

Synonyms

N-(2',6'- Dinethylphenyl)-2-piperidinecarboxamide HCL

UNII:NF8RN1V7VM

Mepivacaine impurity B

Desbutylbupivacaine

(RS)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide,Desbutylbupivacaine

N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide

N-Desbutyl Bupivacaine

MFCD08458869

2',6'-Pipecoloxylidide

2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-

N-(2,6-Dimethylphenyl)piperidine-2-carboxamide

N-(2',6'-Dimethylphenyl)-2-piperidinecarboxamide

(RS)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide

N-(2,6-DIMETHYLPHENYL ) -PIPERIDINE-2-CARBOXYLIC AMIDE

Bupivacaine Impurity 4

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