CAS 306-94-5|Perfluorodecalin

Introduction：Basic information about CAS 306-94-5|Perfluorodecalin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Perfluorodecalin BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles39
8. Synonyms

Common Name	Perfluorodecalin
CAS Number	306-94-5	Molecular Weight	462.078
Density	1.8±0.1 g/cm3	Boiling Point	143.1±40.0 °C at 760 mmHg
Molecular Formula	C₁₀F₁₈	Melting Point	-10ºC
MSDS	ChineseUSA	Flash Point	46.4±19.1 °C

Names

Name	perfluorodecalin
Synonym	More Synonyms

Perfluorodecalin BiologicalActivity

Description	Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears[1][2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Orzalesi N, et al. Experimental short-term tolerance to perfluorodecalin in the rabbit eye: a histopathological study. Curr Eye Res. 1998;17(8):828-835. [2]. Bourke RD, et al. Experimental long-term vitreous replacement with purified and nonpurified perfluorodecalin. Am J Ophthalmol. 1994;118(3):403-404.

Description

Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears[1][2].

Related Catalog

Research Areas >>OthersSignaling Pathways >>Others >>Others

References

[1]. Orzalesi N, et al. Experimental short-term tolerance to perfluorodecalin in the rabbit eye: a histopathological study. Curr Eye Res. 1998;17(8):828-835.

[2]. Bourke RD, et al. Experimental long-term vitreous replacement with purified and nonpurified perfluorodecalin. Am J Ophthalmol. 1994;118(3):403-404.

Chemical & Physical Properties

Density	1.8±0.1 g/cm3
Boiling Point	143.1±40.0 °C at 760 mmHg
Melting Point	-10ºC
Molecular Formula	C₁₀F₁₈
Molecular Weight	462.078
Flash Point	46.4±19.1 °C
Exact Mass	461.971252
LogP	6.03
Vapour density	17.5 (vs air)
Vapour Pressure	6.8±0.3 mmHg at 25°C
Index of Refraction	1.296
InChIKey	UWEYRJFJVCLAGH-UHFFFAOYSA-N
SMILES	FC1(F)C(F)(F)C(F)(F)C2(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C2(F)C1(F)F
Water Solubility	Insoluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ3175000

CHEMICAL NAME :: Naphthalene, decahydrooctadecafluoro-

CAS REGISTRY NUMBER :: 306-94-5

BEILSTEIN REFERENCE NO. :: 2067113

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-F18

MOLECULAR WEIGHT :: 462.10

WISWESSER LINE NOTATION :: L66TJ AF BF BF CF CF DF DF EF EF FF GF GF HF HF IF IF JF JF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >100 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MayGF# Personal Communication from Dr. G.F. May, BNFL Fluorochemicals Ltd., Bldg. 619, Springfields, Salwick, Preston, Lancashire PR4 OXJ. UK, Aug. 25, 1995. Volume(issue)/page/year: 25AUG1995

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >8647 ppm/1H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB81-156911

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PGPKA8 Problemy Gematologii i Perelivaniia Krovi. Problems of Hematology and Blood Transfusion. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1956- Volume(issue)/page/year: 27(10),8,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 90,1513,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4449 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 14 (estimated)

Safety Information

Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R10
Safety Phrases	S24/25-S41
RIDADR	UN 1993 3/PG 3
WGK Germany	3
RTECS	QJ3175000
Packaging Group	III
Hazard Class	3.2
HS Code	2903999090

Customs

HS Code	2903999090
Summary	2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles39

Rapid and reproducible analysis of thiocyanate in real human serum and saliva using a droplet SERS-microfluidic chip.

Biosens. Bioelectron. 62 , 13-8, (2014)

As thiocyanate (SCN(-)) acts as an important biomarker in human health assessment, there remains an urgent need to realize rapid and reproducible analysis of SCN(-) in body fluids. Here, a droplet mic...

Electrochemical droplet-based microfluidics using chip-based carbon paste electrodes for high-throughput analysis in pharmaceutical applications.

Anal. Chim. Acta 883 , 45-54, (2015)

This paper presents the first example of a pharmaceutical application of droplet-based microfluidics coupled with chronoamperometric detection using chip-based carbon paste electrodes (CPEs) for deter...

Passivation of aluminum nanoparticles by plasma-enhanced chemical vapor deposition for energetic nanomaterials.

ACS Appl. Mater. Interfaces 6(10) , 7942-7, (2014)

We have produced passivating coatings on 80-nm aluminum particles by plasma-enhanced chemical vapor deposition (PECVD). Three organic precursors--isopropyl alcohol, toluene, and perfluorodecalin--were...

Synonyms

OCTADECAFLUORODECALIN

perflunafene

perfluorodecahydronaphthalene

F-DC

Naphthalene, 1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-octadecafluorodecahydro-

perfluorodecahydronaphthalin

Perfluorodecalin

pfd

Octadecafluorodecaline

PP 5

EINECS 206-192-4

Perfluoro(decahydronaphthalene)

Octadecafluorodecahydronaphthalene

1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-octadecafluorodecalin

MFCD00010626

perfluorodecaline

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