Introduction：Basic information about CAS 15401-69-1|Berberrubine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Berberrubine |
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| CAS Number | 15401-69-1 | Molecular Weight | 357.788 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C19H16ClNO4 | Melting Point | 245℃ (DEC.) |
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| MSDS | / | Flash Point | / |
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Names
| Name | berberrubine, hydrochloride, dihydrate |
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| Synonym | More Synonyms |
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Berberrubine BiologicalActivity
| Description | Berberrubine chloride is an active metabolite of berberine, attenuates ulcerative colitis in mice model[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Yu XT, et al. Berberrubine attenuates mucosal lesions and inflammation in dextran sodium sulfate-induced colitis in mice. PLoS One. 2018 Mar 14;13(3):e0194069. |
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Chemical & Physical Properties
| Melting Point | 245℃ (DEC.) |
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| Molecular Formula | C19H16ClNO4 |
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| Molecular Weight | 357.788 |
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| Exact Mass | 357.076782 |
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| PSA | 51.80000 |
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| Vapour Pressure | 4.28E-15mmHg at 25°C |
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| Index of Refraction | 1.724 |
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| InChIKey | GYFSYEVKFOOLFZ-UHFFFAOYSA-N |
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| SMILES | COc1ccc2cc3[n+](cc2c1O)CCc1cc2c(cc1-3)OCO2.[Cl-] |
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| Storage condition | 2-8C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DE5399000
- CHEMICAL NAME :
- Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9-hydroxy-10-methoxy-, chloride
- CAS REGISTRY NUMBER :
- 15401-69-1
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C19-H16-N-O4.Cl
- MOLECULAR WEIGHT :
- 357.81
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 22,856,1988
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Synonyms
| berberoline chloride |
| berberrubine |
| 2,3-methylenedioxy-9-hydroxy-10-methoxyprotoberberine chloride |
| Berberrubine chloride |
| 5,6-Dihydro-9-hydroxy-10-methoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride |
| 9-Hydroxy-10-methoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride |
| Beroline chloride |
| berberrubine hydrochloride |
| beberrubine chloride |
| 9-Demethoxy-9-hydroxyberberinium chloride |
| Chileninone |
| hydrochloride berberrubine |
| Berberubine hydrochloride |
| 1,3-Benzodioxolo[5,6-a]benzo[g]quinolizinium, 5,6-dihydro-9-hydroxy-10-methoxy-, chloride (1:1) |
| 9-Berberoline chloride |
