CAS 15641-58-4|2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID
Introduction：Basic information about CAS 15641-58-4|2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID | ||
|---|---|---|---|
| CAS Number | 15641-58-4 | Molecular Weight | 142.19600 |
| Density | 0.999 g/cm3 | Boiling Point | 204.8ºC at 760 mmHg |
| Molecular Formula | C8H14O2 | Melting Point | 120-121 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 97.5ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 2,2,3,3-tetramethylcyclopropanecarboxylic acid |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 0.999 g/cm3 |
|---|---|
| Boiling Point | 204.8ºC at 760 mmHg |
| Melting Point | 120-121 °C(lit.) |
| Molecular Formula | C8H14O2 |
| Molecular Weight | 142.19600 |
| Flash Point | 97.5ºC |
| Exact Mass | 142.09900 |
| PSA | 37.30000 |
| LogP | 1.75320 |
| Vapour Pressure | 0.106mmHg at 25°C |
| Index of Refraction | 1.454 |
| InChIKey | SFHVXKNMCGSLAR-UHFFFAOYSA-N |
| SMILES | CC1(C)C(C(=O)O)C1(C)C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2916209090 |
Customs
| HS Code | 2916209090 |
|---|---|
| Summary | 2916209090 other cyclanic, cyclenic or cyclotherpenic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
Articles4
More Articles| Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue. Epilepsy Res. 98(2-3) , 238-46, (2012) Valproic acid (VPA) is a major antiepileptic drug (AED) that is less potent than other AEDs. 2,2,3,3-Tetramethylcyclopropanecarboxylic acid (TMCA) is an inactive cyclopropyl analogue of VPA that serve... | |
| Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid. J. Med. Chem. 52 , 2233-42, (2009) 2,2,3,3-Tetramethylcyclopropanecarboxylic acid (TMCA, 4) is a cyclic analogue of the antiepileptic drug (AED) valproic acid (VPA) (1). alpha-F, alpha-Cl, alpha-Br, and alpha-methyl derivatives of 4 an... | |
| Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active VPA constitutional isomers and derivatives. Biochem. Pharmacol. 69(10) , 1501-8, (2005) The tumor cells toxicity of the antiepileptic drug valproic acid (VPA) has been associated with the inhibition of histone deacetylases (HDACs). We have assessed, in comparison to VPA, the HDACs inhibi... |
Synonyms
| 2,2,3,3-tetramethylcyclopropane-1-carboxylic acid |
| MFCD00011538 |
| 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXYLIC ACID |
