CAS 118-29-6|2-(Hydroxymethyl)isoindoline-1,3-dione

Introduction：Basic information about CAS 118-29-6|2-(Hydroxymethyl)isoindoline-1,3-dione, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles5
7. Synonyms

Common Name	2-(Hydroxymethyl)isoindoline-1,3-dione
CAS Number	118-29-6	Molecular Weight	177.157
Density	1.5±0.1 g/cm3	Boiling Point	332.0±25.0 °C at 760 mmHg
Molecular Formula	C₉H₇NO₃	Melting Point	147-149 °C(lit.)
MSDS	ChineseUSA	Flash Point	154.6±23.2 °C

Names

Name	N-(hydroxymethyl)phthalimide
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	332.0±25.0 °C at 760 mmHg
Melting Point	147-149 °C(lit.)
Molecular Formula	C₉H₇NO₃
Molecular Weight	177.157
Flash Point	154.6±23.2 °C
Exact Mass	177.042587
PSA	57.61000
LogP	0.76
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.644
InChIKey	MNSGOOCAMMSKGI-UHFFFAOYSA-N
SMILES	O=C1c2ccccc2C(=O)N1CO

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TI5270000

CHEMICAL NAME :: Phthalimide, N-(hydroxymethyl)-

CAS REGISTRY NUMBER :: 118-29-6

BEILSTEIN REFERENCE NO. :: 0140946

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H7-N-O3

MOLECULAR WEIGHT :: 177.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

DOSE :: 300 mg/kg

SEX/DURATION :: female 13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 48(10),64,1983

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	TI5270000
HS Code	29251995

Customs

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles5

Synthesis and anti-inflammatory activity of N-phthalimidomethyl 2,3-dideoxy- and 2,3-unsaturated glycosides.

Carbohydr. Res. 342(9) , 1169-74, (2007)

3,4,6-Tri-O-acetyl-D-galactal, 3,4,6-tri-O-acetyl-D-glucal and 3,6,2',3',4'6'-hexa-O-acetyl-D-lactal were reacted with N-hydroxymethylphthalimide and boron trifluoride etherate to produce the correspo...

Aqueous degradation of N-(hydroxymethyl)phthalimide in the presence of specific and general bases. Kinetic assessment of N-hydroxymethyl derivatives of nitrogen heterocycles as possible prodrugs.

J. Pharm. Biomed. Anal. 7(6) , 685-91, (1989)

The conversion of N-(hydroxymethyl)phthalimide (NHPH) to phthalimide could not be detected within 300 s at pH 9.0, whereas in 0.18 M NaOH complete conversion of NHPH to phthalimide was observed within...

[Effect of hydroxymethylphthalimide on embryogenesis in white rats].

Gig. Sanit. (10) , 64-6, (1983)

Synonyms

1H-Isoindole-1,3(2H)-dione, 2-(hydroxymethyl)-

2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione

PHTHALIMIDOMETHANOL

phthalimidomethyl alcohol

oxymethylphthalimide

N-(Hydroxymethyl)phthalimide

N-Hydroxymethylphthalimide

Phthalimidylmethanol

Hydroxymethyl Phthalimide

Methanol,phthalimido

AURORA KA-454

IFLAB-BB F0777-0575

N-Methylolphthalimide

Phthalimide, N- (hydroxymethyl)-

MFCD00005899

EINECS 204-241-4

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