Introduction：Basic information about CAS 4338-48-1|N6-(2-Hydroxyethyl)adenosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N6-(2-Hydroxyethyl)adenosine |
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| CAS Number | 4338-48-1 | Molecular Weight | 311.29 |
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| Density | 1.88g/cm3 | Boiling Point | 725.8ºC at 760 mmHg |
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| Molecular Formula | C12H17N5O5 | Melting Point | 194-195ºC |
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| MSDS | / | Flash Point | 392.7ºC |
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Names
| Name | (2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol |
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| Synonym | More Synonyms |
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N6-(2-Hydroxyethyl)adenosine BiologicalActivity
| Description | N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. [2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.88g/cm3 |
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| Boiling Point | 725.8ºC at 760 mmHg |
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| Melting Point | 194-195ºC |
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| Molecular Formula | C12H17N5O5 |
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| Molecular Weight | 311.29 |
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| Flash Point | 392.7ºC |
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| Exact Mass | 311.12300 |
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| PSA | 145.78000 |
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| Index of Refraction | 1.806 |
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| InChIKey | BBOCDRLDMQHWJP-WOUKDFQISA-N |
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| SMILES | OCCNc1ncnc2c1ncn2C1OC(CO)C(O)C1O |
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Safety Information
Synonyms
| (2R,3R,4S,5R)-2-[6-(2-hydroxyethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
