CAS 204451-48-9|L-Glutamine-15N2

Introduction:Basic information about CAS 204451-48-9|L-Glutamine-15N2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameL-Glutamine-15N2
CAS Number204451-48-9Molecular Weight148.13100
Density/Boiling Point/
Molecular FormulaC5H1015N2O3Melting Point185ºC (dec.)(lit.)
MSDSChineseUSAFlash Point/

Names

Name(2S)-2,5-bis(azanyl)-5-oxopentanoic acid
SynonymMore Synonyms

L-Glutamine-15N2 BiologicalActivity

DescriptionL-Glutamine-15N2 (L-Glutamic acid 5-amide-15N2) is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
Related CatalogSignaling Pathways >>Apoptosis >>FerroptosisSignaling Pathways >>GPCR/G Protein >>mGluRResearch Areas >>Metabolic Disease
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

Melting Point185ºC (dec.)(lit.)
Molecular FormulaC5H1015N2O3
Molecular Weight148.13100
Exact Mass148.06300
PSA106.41000
LogP0.06440
InChIKeyZDXPYRJPNDTMRX-QLUYOLLXSA-N
SMILESNC(=O)CCC(N)C(=O)O

Safety Information

Hazard CodesXi
RIDADRNONH for all modes of transport
WGK Germany3

Synonyms

MFCD00084216
L-Glutamine-15N2
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