CAS 147127-19-3|(S)-Tenofovir

Introduction:Basic information about CAS 147127-19-3|(S)-Tenofovir, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(S)-Tenofovir
CAS Number147127-19-3Molecular Weight287.21200
Density1.79g/cm3Boiling Point616.1ºC at 760mmHg
Molecular FormulaC9H14N5O4PMelting Point/
MSDS/Flash Point326.4ºC

Names

Name[(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
SynonymMore Synonyms

(S)-Tenofovir BiologicalActivity

Description(S)-Tenofovir ((S)-GS 1278) is the less active S-enantiomer of Tenofovir. Tenofovir is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV)[1].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Others >>Others
References

[1]. Murphy RA, et al. Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity. Int J Mol Sci. 2017 Mar 1;18(3).

Chemical & Physical Properties

Density1.79g/cm3
Boiling Point616.1ºC at 760mmHg
Molecular FormulaC9H14N5O4P
Molecular Weight287.21200
Flash Point326.4ºC
Exact Mass287.07800
PSA146.19000
LogP0.53000
Vapour Pressure4.92E-16mmHg at 25°C
Index of Refraction1.739
InChIKeySGOIRFVFHAKUTI-LURJTMIESA-N
SMILESCC(Cn1cnc2c(N)ncnc21)OCP(=O)(O)O
Storage condition2-8°C

Safety Information

HS Code2933990090

Customs

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

(S)-9-(2-Phosphonomethoxypropyl)adenine
(S)-PMPA
(S)-Tenofovir
Phosphonic acid,P-[[(1S)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-
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