Introduction：Basic information about CAS 42024-98-6|Mazaticol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Mazaticol |
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| CAS Number | 42024-98-6 | Molecular Weight | 405.57 |
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| Density | 1.28g/cm3 | Boiling Point | 528.7ºC at 760 mmHg |
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| Molecular Formula | C21H27NO3S2 | Melting Point | / |
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| MSDS | / | Flash Point | 273.5ºC |
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Names
| Name | (6,6,9-trimethyl-9-azabicyclo[3.3.1]nonan-3-yl) 2-hydroxy-2,2-dithiophen-2-ylacetate |
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| Synonym | More Synonyms |
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Mazaticol BiologicalActivity
| Description | Mazaticol is an anticholinergic agent. Mazaticol blocks the muscarinic acetylcholine receptors and cholinergic nerve activity. Mazaticol is a potent 3H-QNB and 3H-PZ binding inhibitor, can bind to the M2 receptors with high affinity. Mazaticol exhibits inhibitory effects on dopamine uptake in the striatal nerve terminal. Mazaticol can be used for parkinsonian syndrome research[1][2]. |
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| Related Catalog | Signaling Pathways >>Neuronal Signaling >>mAChRSignaling Pathways >>GPCR/G Protein >>mAChRResearch Areas >>Neurological Disease |
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| References | [1]. Niimi Y, et al. Mazaticol for Treating Parkinson. 2020. [2]. Katayama S, et al. Effects of anticholinergic antiparkinsonian drugs on binding of muscarinic receptor subtypes in rat brain. Res Commun Chem Pathol Pharmacol. 1990;69(3):261-270. |
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Chemical & Physical Properties
| Density | 1.28g/cm3 |
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| Boiling Point | 528.7ºC at 760 mmHg |
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| Molecular Formula | C21H27NO3S2 |
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| Molecular Weight | 405.57 |
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| Flash Point | 273.5ºC |
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| Exact Mass | 405.14300 |
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| PSA | 106.25000 |
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| LogP | 4.17800 |
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| Index of Refraction | 1.624 |
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| InChIKey | AMHPTVWBZSYFSS-OAGGEKHMSA-N |
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| SMILES | CN1C2CCC(C)(C)C1CC(OC(=O)C(O)(c1cccs1)c1cccs1)C2 |
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Synonyms
| Mazaticol (INN) |
| 6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl hydroxy(dithiophen-2-yl)acetate |
| Mazaticol |
