CAS 2104-09-8|4-(4-nitro-phenyl)-thiazol-2-ylamine

Introduction：Basic information about CAS 2104-09-8|4-(4-nitro-phenyl)-thiazol-2-ylamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	4-(4-nitro-phenyl)-thiazol-2-ylamine
CAS Number	2104-09-8	Molecular Weight	221.23600
Density	1.459g/cm3	Boiling Point	448.4ºC at 760 mmHg
Molecular Formula	C₉H₇N₃O₂S	Melting Point	283-287ºC
MSDS	ChineseUSA	Flash Point	225ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	4-(4-nitrophenyl)-1,3-thiazol-2-amine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.459g/cm3
Boiling Point	448.4ºC at 760 mmHg
Melting Point	283-287ºC
Molecular Formula	C₉H₇N₃O₂S
Molecular Weight	221.23600
Flash Point	225ºC
Exact Mass	221.02600
PSA	112.97000
LogP	3.40490
Vapour Pressure	3.11E-08mmHg at 25°C
Index of Refraction	1.692
InChIKey	RIKJWJIWXCUKQV-UHFFFAOYSA-N
SMILES	Nc1nc(-c2ccc([N+](=O)[O-])cc2)cs1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ2860000

CHEMICAL NAME :: Thiazole, 2-amino-4-(p-nitrophenyl)-

CAS REGISTRY NUMBER :: 2104-09-8

BEILSTEIN REFERENCE NO. :: 0200321

LAST UPDATED :: 199706

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H7-N3-O2-S

MOLECULAR WEIGHT :: 221.25

WISWESSER LINE NOTATION :: T5N CSJ BZ ER DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2150 mg/kg/13W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - tumors

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 54,841,1975

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9600 mg/kg/46W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - leukemia

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 33,1593,1973

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R22;R36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XJ2860000
HS Code	2934100090

Customs

HS Code	2934100090
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles1

Mass spectrometry of 2-substituted-4-arylthiazoles. II--Identification of microsomal nitroreduction product by mass spectrometry.

Biomed. Mass Spectrom. 9(9) , 376-80, (1982)

Electron impact fragmentation of 2-methyl-4-(4-nitrophenyl)-thiazole and 2-amino-4-(4-nitrophenyl)-thiazoles were studied. Prominent fragment ions result from: (1) elimination of an NO2 radical and of...

Synonyms

2-Thiazolamine,4-(4-nitrophenyl)

4-(4-NITRO-PHENYL)-THIAZOL-2-YLAMINE

2-Amino-4-(4-nitrophenyl)thiazole

4-(4-NITROPHENYL)THIAZOL-2-AMINE

2-Amino-4-(p-nitrophenyl)thiazole

4-(4-NITROPHENYL)-1,3-THIAZOLE-2-YLAMINE

4-(4-Nitrophenyl)-2-thiazolamine

2-AMINO-4-(4-NITROPHENYL)-1,3-THIAZOLE

THIAZOLE,2-AMINO-4-(p-NITROPHENYL)

2-amino-4-(4'-nitrophenyl)-1,3-thiazole

2-THIAZOLAMINE,4-(4-NITROPHENYL)-

4-(4-NITROPHENYL)-2-THIAZOLYLAMINE

4-(4-NITROPHENYL)THIAZOL-2-YLAMINE

MFCD00170222

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