CAS 19660-77-6|Chlorine a6

Introduction:Basic information about CAS 19660-77-6|Chlorine a6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameChlorine a6
CAS Number19660-77-6Molecular Weight596.673
Density1.3±0.1 g/cm3Boiling Point1048.3±65.0 °C at 760 mmHg
Molecular FormulaC34H36N4O6Melting Point/
MSDS/Flash Point587.8±34.3 °C

Names

Namechlorin e6
SynonymMore Synonyms

Chlorine a6 BiologicalActivity

DescriptionChlorin e6 is a photosensitizer. Chlorin e6 has significantly high photosensitizing activity when present in insulin-containing conjugates and thus able to be internalized by receptor-expressing cells. Chlorin E6 effects viability and mitochondrial activity of Leishmania major and Leishmania braziliensis promastigotes[1][2].
Related CatalogResearch Areas >>CancerResearch Areas >>Infection
References

[1]. Pinto JG, et al. Chlorin E6 phototoxicity in L. major and L. braziliensis promastigotes-In vitro study. Photodiagnosis Photodyn Ther. 2016 Sep;15:19-24.

[2]. Akhlynina TV, et al. Nuclear targeting of chlorin e6 enhances its photosensitizing activity. J Biol Chem. 1997 Aug 15;272(33):20328-31.

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point1048.3±65.0 °C at 760 mmHg
Molecular FormulaC34H36N4O6
Molecular Weight596.673
Flash Point587.8±34.3 °C
Exact Mass596.263489
PSA168.20000
LogP6.73
Vapour Pressure0.0±0.3 mmHg at 25°C
Index of Refraction1.643
InChIKeyOYINILBBZAQBEV-PBVYKCSPSA-N
SMILESC=Cc1c(C)c2cc3nc(c(CC(=O)O)c4nc(cc5[nH]c(cc1[nH]2)c(C)c5CC)C(C)=C4C(=O)O)C(CCC(=O)O)C3C
Storage condition-20°C

Synonyms

(17S,18S)-18-(2-carboxyethyl)-20-(carboxymethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-2-carboxylic acid
PHYTOCHLORIN
EINECS 243-209-4
(17S,18S)-18-(2-Carboxyethyl)-20-(carboxymethyl)-7-ethyl-3,8,13,17-tetramethyl-12-vinyl-17,18-dihydro-2-porphyrincarboxylic acid
(17S,18S)-18-(2-Carboxyethyl)-20-(carboxymethyl)-7-ethyl-3,8,13,17-tetramethyl-12-vinyl-17,18-dihydroporphyrin-2-carboxylic acid
Phytochlorin e6
Chlorine e6
21H,22H-Porphine-13-propanoic acid, 17-carboxy-15-(carboxymethyl)-7-ethenyl-2-ethyl-12,13-dihydro-3,8,12,18-tetramethyl-, (12S,13S)-
Phytochlorine e
Chlorine a6
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