CAS 1198-27-2|1-amino-2-naphthol hydrochloride

Introduction:Basic information about CAS 1198-27-2|1-amino-2-naphthol hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name1-amino-2-naphthol hydrochloride
CAS Number1198-27-2Molecular Weight195.64500
Density/Boiling Point336.8ºC at 760mmHg
Molecular FormulaC10H10ClNOMelting Point250 °C (dec.)(lit.)
MSDSChineseUSAFlash Point157.5ºC
Symbol
GHS07, GHS08
Signal WordWarning

Names

Name1-Amino-2-naphthol hydrochloride
SynonymMore Synonyms

Chemical & Physical Properties

Boiling Point336.8ºC at 760mmHg
Melting Point250 °C (dec.)(lit.)
Molecular FormulaC10H10ClNO
Molecular Weight195.64500
Flash Point157.5ºC
Exact Mass195.04500
PSA46.25000
LogP3.51080
Vapour Pressure5.61E-05mmHg at 25°C
InChIKeyDEKREBCFNLUULC-UHFFFAOYSA-N
SMILESCl.Nc1c(O)ccc2ccccc12

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL3335000
CHEMICAL NAME :
2-Naphthol, 1-amino-, hydrochloride
CAS REGISTRY NUMBER :
1198-27-2
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C10-H9-N-O.Cl-H
MOLECULAR WEIGHT :
195.66
WISWESSER LINE NOTATION :
L66J BZ CQ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
500 ug/well/16H
REFERENCE :
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 15,219,1976

Safety Information

Symbol
GHS07, GHS08
Signal WordWarning
Hazard StatementsH302 + H312 + H332-H315-H319-H335-H351
Precautionary StatementsP261-P280-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXn:Harmful;
Risk PhrasesR20/21/22;R36/37/38;R40
Safety PhrasesS26-S27-S36/37/39
RIDADRNONH for all modes of transport
WGK Germany3
RTECSQL3335000
HS Code2922299090

Customs

HS Code2922299090
Summary2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles8

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Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora.

Appl. Environ. Microbiol. 73(23) , 7759-62, (2007)

The rates of metabolism of Sudan I and II and Para Red by human intestinal microflora were high compared to those of Sudan III and IV under anaerobic conditions. Metabolites of the dyes were identifie...

Evaluation of impact of exposure of Sudan azo dyes and their metabolites on human intestinal bacteria.

Anaerobe 18(4) , 445-53, (2012)

Sudan azo dyes are banned for food usage in most countries, but they are illegally used to maintain or enhance the color of food products due to low cost, bright staining, and wide availability of the...

Effects of Orange II and Sudan III azo dyes and their metabolites on Staphylococcus aureus.

J. Ind. Microbiol. Biotechnol. 38(10) , 1729-38, (2011)

Azo dyes are widely used in the plastic, paper, cosmetics, food, and pharmaceutical industries. Some metabolites of these dyes are potentially genotoxic. The toxic effects of azo dyes and their potent...

Synonyms

1-Amino-2-naphthol Hydrochloride
EINECS 214-830-8
1-Amino-2-naphtholhydrochloride
MFCD00012561
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