CAS 555-55-5|HISPIDIN
| Common Name | HISPIDIN | ||
|---|---|---|---|
| CAS Number | 555-55-5 | Molecular Weight | 246.21500 |
| Density | 1.657g/cm3 | Boiling Point | 554.2ºC at 760 mmHg |
| Molecular Formula | C13H10O5 | Melting Point | 312-315ºC |
| MSDS | ChineseUSA | Flash Point | 220.1ºC |
Names
| Name | hispidin |
|---|---|
| Synonym | More Synonyms |
HISPIDIN BiologicalActivity
| Description | Hispidin, a PKC inhibitor and a phenolic compound from Phellinus linteus, has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Epigenetics >>PKCResearch Areas >>Cardiovascular DiseaseResearch Areas >>Metabolic DiseaseSignaling Pathways >>TGF-beta/Smad >>PKC |
| References | [1]. Kim DE, et al. The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. Exp Cell Res. 2014 Oct 1;327(2):264-75. |
Chemical & Physical Properties
| Density | 1.657g/cm3 |
|---|---|
| Boiling Point | 554.2ºC at 760 mmHg |
| Melting Point | 312-315ºC |
| Molecular Formula | C13H10O5 |
| Molecular Weight | 246.21500 |
| Flash Point | 220.1ºC |
| Exact Mass | 246.05300 |
| PSA | 90.90000 |
| LogP | 1.92700 |
| Index of Refraction | 1.854 |
| InChIKey | SGJNQVTUYXCBKH-HNQUOIGGSA-N |
| SMILES | O=c1cc(O)cc(C=Cc2ccc(O)c(O)c2)o1 |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles32
More Articles| Anti-inflammatory activity of mushroom-derived hispidin through blocking of NF-κB activation. J. Sci. Food Agric. 95 , 2482-6, (2015) Hispidin, a polyphenol compound mainly derived from the valuable medicinal mushroom Phellinus species, has been found to possess distinct biological effects. However, the anti-inflammatory potential o... | |
| Anticancer activity of hispidin via reactive oxygen species-mediated apoptosis in colon cancer cells. Anticancer Res. 34(8) , 4087-93, (2014) Few studies have been performed on the anticancer activity of hispidin, a phenolic compound produced from the medicinal mushroom Phellinus linteus. Herein, we studied hispidin-induced apoptosis, which... | |
| The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. Exp. Cell Res. 327(2) , 264-75, (2014) Hispidin, a phenolic compound from Phellinus linteus (a medicinal mushroom), has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties. However, the cardi... |
Synonyms
| 6-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxypyran-2-one |
| 6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone |
