Introduction：Basic information about CAS 536-25-4|Orthocaine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Orthocaine |
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| CAS Number | 536-25-4 | Molecular Weight | 167.162 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 326.8±27.0 °C at 760 mmHg |
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| Molecular Formula | C8H9NO3 | Melting Point | 141-143ºC |
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| MSDS | USA | Flash Point | 151.4±23.7 °C |
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Names
| Name | Methyl 3-amino-4-hydroxybenzoate |
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| Synonym | More Synonyms |
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Orthocaine BiologicalActivity
| Description | Orthocaine is a local anesthetic agent (extracted from patent WO2002089849A1)[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| References | [1]. Gary W. Cleary, et al. Compositions and delivery systems for administration of a local anesthetic agent. Patent WO2002089849A1. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 326.8±27.0 °C at 760 mmHg |
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| Melting Point | 141-143ºC |
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| Molecular Formula | C8H9NO3 |
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| Molecular Weight | 167.162 |
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| Flash Point | 151.4±23.7 °C |
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| Exact Mass | 167.058243 |
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| PSA | 72.55000 |
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| LogP | 0.92 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.606 |
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| InChIKey | VNQABZCSYCTZMS-UHFFFAOYSA-N |
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| SMILES | COC(=O)c1ccc(O)c(N)c1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DG2750000
- CHEMICAL NAME :
- Benzoic acid, 3-amino-4-hydroxy-, methyl ester
- CAS REGISTRY NUMBER :
- 536-25-4
- BEILSTEIN REFERENCE NO. :
- 0608715
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C8-H9-N-O3
- MOLECULAR WEIGHT :
- 167.18
- WISWESSER LINE NOTATION :
- ZR DQ EVO1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | 22 |
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| HS Code | 2922509090 |
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Customs
| HS Code | 2922509090 |
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| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Aminobenz |
| Methyl 3-amino-4-hydroxybenzoate |
| 2-amino-4-methoxycarbonylphenol |
| MFCD00017095 |
| Orthoform |
| BENZOIC ACID,3-AMINO-4-HYDROXY-,METHYL ESTER |
| Orthoform New |
| Orthoderm |
| Orthocaine |
| Methyl m-amino-p-hydroxybenzoate |
| Methyl 4-hydroxy-3-aminobenzoate |
| Benzoic acid, 3-amino-4-hydroxy-, methyl ester |
| Methyl3-Amino-4-hydroxybenzoate |
| 4-hydroxy-3-amino-benzoic acid methyl ester |
| 3-Amino-4-hydroxybenzoic acid methyl ester |
| EINECS 208-627-3 |
