CAS 2093-20-1|Ethyl acetate-PEG1

Introduction:Basic information about CAS 2093-20-1|Ethyl acetate-PEG1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameEthyl acetate-PEG1
CAS Number2093-20-1Molecular Weight148.15700
Density/Boiling Point/
Molecular FormulaC6H12O4Melting Point/
MSDS/Flash Point/

Names

Name2-(2-Hydroxyethoxy)ethyl acetate

Ethyl acetate-PEG1 BiologicalActivity

DescriptionEthyl acetate-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Molecular FormulaC6H12O4
Molecular Weight148.15700
Exact Mass148.07400
PSA55.76000
Vapour Pressure0.0121mmHg at 25°C
InChIKeyXXXFZKQPYACQLD-UHFFFAOYSA-N
SMILESCC(=O)OCCOCCO

Safety Information

HS Code2915390090

Customs

HS Code2915390090
Summary2915390090. esters of acetic acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:5.5%. General tariff:30.0%
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