CAS 1517-05-1|Azido-PEG1

Introduction:Basic information about CAS 1517-05-1|Azido-PEG1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameAzido-PEG1
CAS Number1517-05-1Molecular Weight325.795
Density1.3±0.1 g/cm3Boiling Point411.7±45.0 °C at 760 mmHg
Molecular FormulaC17H16ClN5Melting Point/
MSDS/Flash Point202.8±28.7 °C

Names

Name2-Azidoethanol
SynonymMore Synonyms

Azido-PEG1 BiologicalActivity

DescriptionAzido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point411.7±45.0 °C at 760 mmHg
Molecular FormulaC17H16ClN5
Molecular Weight325.795
Flash Point202.8±28.7 °C
Exact Mass325.109436
PSA69.98000
LogP5.39
Vapour Pressure0.0±1.0 mmHg at 25°C
Index of Refraction1.698
InChIKeyBSULWPSUVMOMAN-UHFFFAOYSA-N
SMILES[N-]=[N+]=NCCO

Safety Information

HS Code2929909090

Customs

HS Code2929909090
Summary2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Synonyms

4-Chloro-6-[2-(diphenylmethyl)hydrazino]-5-pyrimidinamine
5-Pyrimidinamine, 4-chloro-6-[2-(diphenylmethyl)hydrazinyl]-
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