CAS 140-10-3|Cinnamic acid
| Common Name | Cinnamic acid | ||
|---|---|---|---|
| CAS Number | 140-10-3 | Molecular Weight | 148.159 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 265.0±0.0 °C at 760 mmHg |
| Molecular Formula | C9H8O2 | Melting Point | 133 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 189.5±9.6 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | trans-cinnamic acid |
|---|---|
| Synonym | More Synonyms |
Cinnamic acid BiologicalActivity
| Description | trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>InfectionNatural Products >>Phenylpropanoids |
| Target | Bacterial[1] |
| In Vitro | trans-Cinnamic acid is an antimicrobial activity, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1. trans-cinnamic acid shows moderate inhibition on the rainbow trout intestinal isolates A. sobria SY-AS3 and S. baltica, SY-S145, gill isolate F. spartansii SY-FS1 and fish pathogens A. salmonicida ATCC 33658, Listonella anguillarum, SY-L24, V. crassostreae SY-VC10 and Y. ruckeri E42. trans-cinnamic acid is more effective on bacteria when the pH of the culture media is not neutralized[1]. |
| References | [1]. Yilmaz S, et al. Antimicrobial activity of trans-cinnamic acid and commonly used antibiotics against important fish pathogens and nonpathogenic isolates. J Appl Microbiol. 2018 Sep 4. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 265.0±0.0 °C at 760 mmHg |
| Melting Point | 133 °C(lit.) |
| Molecular Formula | C9H8O2 |
| Molecular Weight | 148.159 |
| Flash Point | 189.5±9.6 °C |
| Exact Mass | 148.052429 |
| PSA | 37.30000 |
| LogP | 2.41 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.616 |
| InChIKey | WBYWAXJHAXSJNI-VOTSOKGWSA-N |
| SMILES | O=C(O)C=Cc1ccccc1 |
| Storage condition | Store at RT. |
| Water Solubility | 0.4 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | GD7850000 |
| HS Code | 29163900 |
Customs
| HS Code | 29163900 |
|---|
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Synonyms
| trans-3-Phenylacrylic acid,Cinnamic acid |
| trans-Cinnamic acid |
| Cinnamic acid |
| (2E)-3-Phenylacrylic acid |
| EINECS 205-398-1 |
| MFCD00004369 |
| trans-3-Phenylacrylic Acid |
| Cinnamyl acid |
