CAS 19210-12-9|Harpagoside

Introduction：Basic information about CAS 19210-12-9|Harpagoside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Harpagoside BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles27
6. Synonyms

Common Name	Harpagoside
CAS Number	19210-12-9	Molecular Weight	494.488
Density	1.5±0.1 g/cm3	Boiling Point	720.7±60.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₀O₁₁	Melting Point	120ºC (dec.)
MSDS	ChineseUSA	Flash Point	244.3±26.4 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	Harpagoside
Synonym	More Synonyms

Harpagoside BiologicalActivity

Description	Harpagoside is isolated from Harpagophytum procumbens (Hp). Harpagoside has inhibitory effects on COX-1 and COX-2 activity and inhibits NO production[1].
Related Catalog	Signaling Pathways >>Immunology/Inflammation >>COX
Target	COX-1 COX-2
References	[1]. Anauate MC, et al. Effect of isolated fractions of Harpagophytum procumbens D.C. (devil's claw) on COX-1, COX-2 activity and nitric oxide production on whole-blood assay. Phytother Res. 2010 Sep;24(9):1365-9.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	720.7±60.0 °C at 760 mmHg
Melting Point	120ºC (dec.)
Molecular Formula	C₂₄H₃₀O₁₁
Molecular Weight	494.488
Flash Point	244.3±26.4 °C
Exact Mass	494.178802
PSA	175.37000
LogP	-0.92
Vapour Pressure	0.0±2.4 mmHg at 25°C
Index of Refraction	1.660
InChIKey	KVRQGMOSZKPBNS-FMHLWDFHSA-N
SMILES	CC1(OC(=O)C=Cc2ccccc2)CC(O)C2(O)C=COC(OC3OC(CO)C(O)C(O)C3O)C12
Storage condition	2-8°C

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	22-45
RIDADR	UN 3172

Articles27

What the devil is in your phytomedicine? Exploring species substitution in Harpagophytum through chemometric modeling of 1H-NMR and UHPLC-MS datasets.

Phytochemistry 106 , 104-15, (2014)

Harpagophytum procumbens (Pedaliaceae) and its close taxonomical ally Harpagophytum zeyheri, indigenous to southern Africa, are being harvested for exportation to Europe where phytomedicines are devel...

Metabolic differentiations and classification of Verbascum species by NMR-based metabolomics.

Phytochemistry 72(16) , 2045-51, (2011)

The genus Verbascum L. (mulleins) comprises of about 360 species of flowering plants in the Scrophulariaceae family. Mulleins have been used in the traditional folk medicine for centuries, for treatme...

[Simultaneous determination of five constituents in Scrophularia ningpoensis by HPLC].

Zhongguo Zhong Yao Za Zhi 36(6) , 709-11, (2011)

To develop an HPLC method for the simultaneous quantitation of five constituents in Scrophularia ningpoensis.Samples were analyzed on an Agilent SB-C18 column(4.6 mm x 250 mm, 5 microm) eluted with ac...

Synonyms

8'-CINNAMOYLHARPAGIDE

1-(Hexopyranosyloxy)-4a,5-dihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-7-yl 3-phenylacrylate

2-Propenoic acid, 3-phenyl-, 1-(hexopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methylcyclopenta[c]pyran-7-yl ester

Harpagosid

MFCD00017415

8-O-E CINNAMOYL HARPAGIDE

Harpogoside

Einecs 242-881-6

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