CAS 84104-71-2|Wilforlide A

Introduction：Basic information about CAS 84104-71-2|Wilforlide A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Wilforlide A BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Wilforlide A
CAS Number	84104-71-2	Molecular Weight	454.684
Density	1.1±0.1 g/cm3	Boiling Point	555.0±50.0 °C at 760 mmHg
Molecular Formula	C₃₀H₄₆O₃	Melting Point	318 °C
MSDS	/	Flash Point	208.6±22.9 °C

Names

Name	wilforlide a
Synonym	More Synonyms

Wilforlide A BiologicalActivity

Description	Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. IC50 value:Target:In vitro:In vivo: Carrageenan-induced rat pedal swelling, tampon-induced rat granulation, and mice ear inhibition rate of swelling trail results show that high-dose wilforlide A has obvious anti-inflammatory effect, but has no significant immune suppressive activity [1].
Related Catalog	Signaling Pathways >>Others >>OthersNatural Products >>Terpenoids and GlycosidesResearch Areas >>Inflammation/Immunology
References	[1]. Mei Xue, et al. Comparative study on the anti-inflammatory and immune suppressive effect of Wilforlide A. Fitoterapia Volume 81, Issue 8, December 2010, Pages 1109–1112 [2]. HU Jian-lin, et al. Determination of Wilforlide A in Tripterygium hypoglaucum (Levl.) Hutch by HPLC. Journal of Kunming Medical College, 2010-07

Description

Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. IC50 value:Target:In vitro:In vivo: Carrageenan-induced rat pedal swelling, tampon-induced rat granulation, and mice ear inhibition rate of swelling trail results show that high-dose wilforlide A has obvious anti-inflammatory effect, but has no significant immune suppressive activity [1].

Related Catalog

Signaling Pathways >>Others >>OthersNatural Products >>Terpenoids and GlycosidesResearch Areas >>Inflammation/Immunology

References

[1]. Mei Xue, et al. Comparative study on the anti-inflammatory and immune suppressive effect of Wilforlide A. Fitoterapia Volume 81, Issue 8, December 2010, Pages 1109–1112

[2]. HU Jian-lin, et al. Determination of Wilforlide A in Tripterygium hypoglaucum (Levl.) Hutch by HPLC. Journal of Kunming Medical College, 2010-07

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	555.0±50.0 °C at 760 mmHg
Melting Point	318 °C
Molecular Formula	C₃₀H₄₆O₃
Molecular Weight	454.684
Flash Point	208.6±22.9 °C
Exact Mass	454.344696
PSA	46.53000
LogP	7.47
Vapour Pressure	0.0±3.4 mmHg at 25°C
Index of Refraction	1.563
InChIKey	HHQJBWYXBWOFJY-VYXRQJSZSA-N
SMILES	CC12CC(OC1=O)C1(C)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C1C2

Safety Information

Hazard Codes	C

Synonyms

Olean-12-en-29-one, 22,29-epoxy-3-hydroxy-, (3β,22α)-

WOLFORLIDE A

(3β,22α)-3-Hydroxy-22,29-epoxyolean-12-en-29-one

Regelide

Wilforlide

WilforlideA

abruslactone A

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