Introduction：Basic information about CAS 1156-78-1|2',4',5,7-Tetrahydroxyisoflavone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2',4',5,7-Tetrahydroxyisoflavone |
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| CAS Number | 1156-78-1 | Molecular Weight | 286.24 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 619.1±55.0 °C at 760 mmHg |
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| Molecular Formula | C15H10O6 | Melting Point | / |
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| MSDS | / | Flash Point | 240.7±25.0 °C |
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Names
| Name | 2'-hydroxygenistein |
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| Synonym | More Synonyms |
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2',4',5,7-Tetrahydroxyisoflavone BiologicalActivity
| Description | 2′-Hydroxygenistein is a natural product that can be isolated from Crotalaria pallida and C. assamica. 2′-Hydroxygenistein shows anti-inflammatory activity. 2′-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of β-glucuronidase and lysozyme from rat neutrophils, with IC50 values of 5.9 ± 1.4 and 9.7 ± 3.5 μM, respectively[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Ko HH, Weng JR, Tsao LT, Yen MH, Wang JP, Lin CN. Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. Bioorg Med Chem Lett. 2004 Feb 23;14(4):1011-4. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 619.1±55.0 °C at 760 mmHg |
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| Molecular Formula | C15H10O6 |
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| Molecular Weight | 286.24 |
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| Flash Point | 240.7±25.0 °C |
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| Exact Mass | 286.047729 |
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| PSA | 111.13000 |
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| LogP | 2.99 |
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| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
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| Index of Refraction | 1.768 |
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| InChIKey | GSSOWCUOWLMMRJ-UHFFFAOYSA-N |
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| SMILES | O=c1c(-c2ccc(O)cc2O)coc2cc(O)cc(O)c12 |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2914501900 |
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Customs
| HS Code | 2914501900 |
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| Summary | 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
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Synonyms
| 3-(2,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one |
| 2',4',5,7-Tetrahydroxyisoflavone |
| Isoflavone, 2',4',5,7-tetrahydroxy- |
| 2'-HYDROXYGENISTEIN |
| 4H-1-Benzopyran-4-one, 3-(2,4-dihydroxyphenyl)-5,7-dihydroxy- |
| 5,7,2',4'-Tetrahydroxy-isoflavone |
| 3-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one |
| MFCD00075967 |
