CAS 1121-89-7|Glutarimide

Introduction：Basic information about CAS 1121-89-7|Glutarimide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles29
7. Synonyms

Common Name	Glutarimide
CAS Number	1121-89-7	Molecular Weight	113.115
Density	1.2±0.1 g/cm3	Boiling Point	288.0±9.0 °C at 760 mmHg
Molecular Formula	C₅H₇NO₂	Melting Point	155-157 °C(lit.)
MSDS	ChineseUSA	Flash Point	152.3±18.9 °C

Names

Name	piperidine-2,6-dione
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	288.0±9.0 °C at 760 mmHg
Melting Point	155-157 °C(lit.)
Molecular Formula	C₅H₇NO₂
Molecular Weight	113.115
Flash Point	152.3±18.9 °C
Exact Mass	113.047676
PSA	46.17000
LogP	-0.04
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.471
InChIKey	KNCYXPMJDCCGSJ-UHFFFAOYSA-N
SMILES	O=C1CCCC(=O)N1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MA4000000

CHEMICAL NAME :: Glutarimide

CAS REGISTRY NUMBER :: 1121-89-7

BEILSTEIN REFERENCE NO. :: 0110052

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H7-N-O2

MOLECULAR WEIGHT :: 113.13

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 173,115,1968

Safety Information

Hazard Codes	Xi:Irritant;
Risk Phrases	R36
Safety Phrases	S37/39-S26
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	MA4000000
HS Code	2925190090

Customs

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles29

Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.

Biochemistry 53(49) , 7854-65, (2014)

Lactimidomycin (LTM, 1) and iso-migrastatin (iso-MGS, 2) belong to the glutarimide-containing polyketide family of natural products. We previously cloned and characterized the mgs biosynthetic gene cl...

Iso-migrastatin congeners from Streptomyces platensis and generation of a glutarimide polyketide library featuring the dorrigocin, lactimidomycin, migrastatin, and NK30424 scaffolds.

J. Am. Chem. Soc. 127(34) , 11930-1, (2005)

Iso-Migrastatin (10) has been shown to be the main natural product of Streptomyces platensis, which undergoes a facile, H2O-mediated rearrangement into dorrigocin A (2), 13-epi-dorrigocin A (11), dorr...

Enantiomerization mechanism of thalidomide and the role of water and hydroxide ions.

Chemistry 18(45) , 14305-13, (2012)

The significance of the molecular chirality of drugs has been widely recognized due to the thalidomide tragedy. Most of the new drugs reaching the market today are single enantiomers, rather than race...

Synonyms

2,6-Piperidinedione

GlutariMide 25GR

Glutarimide

piperidin-1-yl-2,6-dione

EINECS 214-340-4

2,6-Diketopiperidine2,6-Piperidinedione

Piperidine-2,6-dione

MFCD00006670

2,6-dioxopiperidine

2,6-Piperidinedione (9CI)

L-glutarimide

2,6-DIKETOPIPERIDINE

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