CAS 914-00-1|methacycline

CHEMICAL IDENTIFICATION

RTECS NUMBER :

QI9275000

CHEMICAL NAME :

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro- 3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-

CAS REGISTRY NUMBER :

914-00-1

LAST UPDATED :

199506

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C22-H22-N2-O8

MOLECULAR WEIGHT :

442.46

WISWESSER LINE NOTATION :

L E6 C666 BV FV MY CU GU LHTT&&J DQ EQ GVZ HQ IN1&1 KQ MU1 RQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

660 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :

DNA inhibition

TEST SYSTEM :

Human Lymphocyte

DOSE/DURATION :

3750 ug/L

REFERENCE :

BCPHBM British Journal of Clinical Pharmacology. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1974- Volume(issue)/page/year: 16,127,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1538 No. of Facilities: 11 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1150 (estimated) No. of Female Employees: 591 (estimated)