Introduction：Basic information about CAS 1438-30-8|Antibiotic 1142, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Antibiotic 1142 |
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| CAS Number | 1438-30-8 | Molecular Weight | 430.46400 |
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| Density | 1.52g/cm3 | Boiling Point | 544.74°C (rough estimate) |
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| Molecular Formula | C18H26N10O3 | Melting Point | 171-173℃ |
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| MSDS | / | Flash Point | / |
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Names
| Name | netropsin |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.52g/cm3 |
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| Boiling Point | 544.74°C (rough estimate) |
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| Melting Point | 171-173℃ |
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| Molecular Formula | C18H26N10O3 |
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| Molecular Weight | 430.46400 |
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| Exact Mass | 430.21900 |
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| PSA | 208.93000 |
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| LogP | 1.62120 |
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| Appearance of Characters | powder | faint yellow |
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| Vapour Pressure | 1.75E-23mmHg at 25°C |
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| Index of Refraction | 1.6500 (estimate) |
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| InChIKey | IDBIFFKSXLYUOT-UHFFFAOYSA-N |
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| SMILES | Cn1cc(NC(=O)c2cc(NC(=O)CN=C(N)N)cn2C)cc1C(=O)NCCC(=N)N |
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| Storage condition | −20°C |
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| Water Solubility | H2O: 1 mg/mL |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DW2973000
- CHEMICAL NAME :
- N,4'-Bi(pyrrole-2-carboxamide), N'-(2-carbamoylethyl)-4-((2-guanidinoacetimidoyl)amin o)-1,1'- dimethyl-
- CAS REGISTRY NUMBER :
- 1438-30-8
- BEILSTEIN REFERENCE NO. :
- 0376913
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C18-H26-N10-O3
- MOLECULAR WEIGHT :
- 430.54
- WISWESSER LINE NOTATION :
- T5NJ A1 BVM2VZ EMV- BT5NJ A1 DMYUM&1MYZUM
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 500 umol/L
- REFERENCE :
- MLBRBU Molecular Biology Reports. (Dr. W. Junk Pub., POB 163, 3300 AD Dordrect, Netherlands) V.1- 1973- Volume(issue)/page/year: 2,135,1975
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Safety Information
| Hazard Codes | Xn: Harmful; |
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| Risk Phrases | R22 |
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| Safety Phrases | S36 |
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| RIDADR | UN 2811 6.1/PG 3 |
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| WGK Germany | 3 |
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| RTECS | DW2973000 |
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Synonyms
| 4-{4-[(N-carbamimidoyl-glycyl)-amino]-1-methyl-pyrrole-2-carbonylamino}-1-methyl-pyrrole-2-carboxylic acid-(2-carbamimidoyl-ethylamide) |
| t1384 |
| Netropsin dihydrochloride |
| ia887 |
| 4-{4-[(N-Carbamimidoyl-glycyl)-amino]-1-methyl-pyrrol-2-carbonylamino}-1-methyl-pyrrol-2-carbonsaeure-(2-carbamimidoyl-aethylamid) |
| ch-777-a |
| Congocidin Sinanomycin |
| congocidin |
| ultrapuregrade |
| 2814-a |
| antibiotic1142 |
