Introduction：Basic information about CAS 216757-29-8|Ac-Ile-Glu-Pro-Asp-pNA, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ac-Ile-Glu-Pro-Asp-pNA |
|---|
| CAS Number | 216757-29-8 | Molecular Weight | 634.635 |
|---|
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1096.9±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C28H38N6O11 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 617.2±34.3 °C |
|---|
Names
| Name | (4S)-4-[[(2S,3S)-2-acetamido-3-methylpentanoyl]amino]-5-[(2S)-2-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-oxopentanoic acid |
|---|
| Synonym | More Synonyms |
|---|
Ac-Ile-Glu-Pro-Asp-pNA BiologicalActivity
| Description | N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a granzyme B substrate that allows accurate measurement of granzyme B activity[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
|---|
| References | [1]. Kristina Fritsch, et al. Suppression of granzyme B activity and caspase-3 activation in leukaemia cells constitutively expressing the protease inhibitor 9. Ann Hematol. 2013 Dec;92(12):1603-9. |
|---|
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|
| Boiling Point | 1096.9±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C28H38N6O11 |
|---|
| Molecular Weight | 634.635 |
|---|
| Flash Point | 617.2±34.3 °C |
|---|
| Exact Mass | 634.259827 |
|---|
| PSA | 257.13000 |
|---|
| LogP | 2.01 |
|---|
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
|---|
| Index of Refraction | 1.592 |
|---|
| InChIKey | YXEIIOVAGGAMCZ-NYMCBPKFSA-N |
|---|
| SMILES | CCC(C)C(NC(C)=O)C(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NC(CC(=O)O)C(=O)Nc1ccc([N+](=O)[O-])cc1 |
|---|
| Storage condition | -20°C |
|---|
Safety Information
Synonyms
| L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-nitrophenyl)- |
| N-Acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-nitrophenyl)-L-α-asparagine |
