Introduction：Basic information about CAS 112173-48-5|Angiogenin (108-123), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Angiogenin (108-123) |
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| CAS Number | 112173-48-5 | Molecular Weight | 1878.10000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C83H132N26O24 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Angiogenin Fragment (108-123) |
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| Synonym | More Synonyms |
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Angiogenin (108-123) BiologicalActivity
| Description | Angiogenin Fragment (108-123) is a C-terminal segment 108-123 of Angiogenin that inhibits the enzymatic and biological activities of Angiogenin[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
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| In Vitro | Angiogenin Fragment (108-123) inhibits the initial rate of degradation of tRNA catalyzed by angiogenin in a concentration dependent manner yielding an apparent Ki value of 278 μM. Angiogenin Fragment (108-123) also inhibits nuclease activity of angiogenin when tRNA is the substrate. Furthermore, Angiogenin Fragment (108-123) significantly decreases neovascularization elicited by angiogenin in the chick chorioallantoic membrane assay[1]. |
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| References | [1]. S M Rybak, et al. C-terminal angiogenin peptides inhibit the biological and enzymatic activities of angiogenin. Biochem Biophys Res Commun. 1989 Jul 14;162(1):535-43. |
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Chemical & Physical Properties
| Molecular Formula | C83H132N26O24 |
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| Molecular Weight | 1878.10000 |
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| Exact Mass | 1876.99000 |
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| PSA | 815.73000 |
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| LogP | 1.75640 |
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Synonyms
| angiogenin fragment 108-123 |
| glu-asn-gly-leu-pro-val-his-leu-asp-gln-ser-ile-phe-arg-arg-pro |
| angiogenin (108-123) |
| h-glu-asn-gly-leu-pro-val-his-leu-asp-gln-ser-ile-phe-arg-arg-pro-oh |
