Introduction：Basic information about CAS 15266-88-3|Cyclo(-Gly-His), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cyclo(-Gly-His) |
|---|
| CAS Number | 15266-88-3 | Molecular Weight | 194.19 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C8H10N4O2 | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | Cyclo(-Gly-His) |
|---|
| Synonym | More Synonyms |
|---|
Cyclo(-Gly-His) BiologicalActivity
| Description | Cyclo(Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo(Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC50 values of 1.699 mM and 0.358 mM, respectively. Cyclo(Gly-His) can be used for the research of drug delivery systems[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
|---|
| Target | IC50: 1.699 mM (HeLa cell) and 0.358 mM (MCF-7 cell)[1]. |
|---|
| In Vitro | Cyclo(Gly-His) 对 HeLa 和 MCF-7 细胞具有细胞毒性，IC50 值分别为 1.699 mM 和 0.358 mM[1]。 |
|---|
| References | [1]. Kilian G, et al. Anticancer activity of the liposome-encapsulated cyclic dipeptides, cyclo(His-Gly) and cyclo(His-Ala). Pharmazie. 2013;68(3):207-211. |
|---|
Chemical & Physical Properties
| Molecular Formula | C8H10N4O2 |
|---|
| Molecular Weight | 194.19 |
|---|
| Exact Mass | 194.08000 |
|---|
| PSA | 86.88000 |
|---|
| InChIKey | FYFJTCMGWLBLPG-LURJTMIESA-N |
|---|
| SMILES | O=C1CNC(=O)C(Cc2cnc[nH]2)N1 |
|---|
Safety Information
Customs
| HS Code | 2933990090 |
|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|---|
Synonyms
| (S)-3-(1H-Imidazol-4-ylmethyl)-2,5-piperazinedione |
| CYCLO(GLY-L-HIS) |
| cyclo-Gly-His |
| cyclo-(glycyl-L-histidyl) |
