CAS 2140-77-4|N-Methylguanosine
| Common Name | N-Methylguanosine | ||
|---|---|---|---|
| CAS Number | 2140-77-4 | Molecular Weight | 297.267 |
| Density | 2.0±0.1 g/cm3 | Boiling Point | 709.5ºC at 760mmHg |
| Molecular Formula | C11H15N5O5 | Melting Point | 233 °C (decomp)(Solv: water (7732-18-5)) |
| MSDS | ChineseUSA | Flash Point | 382.9ºC |
Names
| Name | n2-methylguanosine |
|---|---|
| Synonym | More Synonyms |
N-Methylguanosine BiologicalActivity
| Description | N2-methylguanosine is a modified nucleoside that occurs at several specific locations in many tRNA's. |
|---|---|
| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
| References | [1]. Ginell SL, et al. Conformation of N2-methylguanosine, a modified nucleoside of tRNA. Biochem Biophys Res Commun. 1978 Oct 30;84(4):886-94. |
Chemical & Physical Properties
| Density | 2.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 709.5ºC at 760mmHg |
| Melting Point | 233 °C (decomp)(Solv: water (7732-18-5)) |
| Molecular Formula | C11H15N5O5 |
| Molecular Weight | 297.267 |
| Flash Point | 382.9ºC |
| Exact Mass | 297.107330 |
| PSA | 145.52000 |
| LogP | -3.09 |
| Vapour Pressure | 3.99E-21mmHg at 25°C |
| Index of Refraction | 1.850 |
| Storage condition | 2-8°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles33
More Articles| Exometabolom analysis of breast cancer cell lines: Metabolic signature. Sci. Rep. 5 , 13374, (2015) Cancer cells show characteristic effects on cellular turnover and DNA/RNA modifications leading to elevated levels of excreted modified nucleosides. We investigated the molecular signature of differen... | |
| Artificial receptors for the extraction of nucleoside metabolite 7-methylguanosine from aqueous media made by molecular imprinting. J. Chromatogr. A. 1365 , 12-8, (2014) A series of imprinted polymers targeting nucleoside metabolites, prepared using a template analogue approach, are presented. These were prepared following selection of the optimum functional monomer b... | |
| Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase. Proc. Natl. Acad. Sci. U. S. A. 106 , 3484-3489, (2009) The N7-methylguanosine (m7G) cap is the defining structural feature of eukaryotic mRNAs. Most eukaryotic viruses that replicate in the cytoplasm, including coronaviruses, have evolved strategies to ca... |
Synonyms
| 2-Methylguanosine |
| Guanosine, N-methyl- |
| N-Methylguanosine |
| Guanosine,N-methyl |
| 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-methylamino-3H-purin-6-one |
| 2-N-Methylguanosine |
| N(2)-Methylguanosine |
