CAS 54662-30-5|12-deoxyphorbol 13-phenylacetate 20-acetate
| Common Name | 12-deoxyphorbol 13-phenylacetate 20-acetate | ||
|---|---|---|---|
| CAS Number | 54662-30-5 | Molecular Weight | 508.60300 |
| Density | 1.29g/cm3 | Boiling Point | 635.7ºC at 760 mmHg |
| Molecular Formula | C30H36O7 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 204.3ºC |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | 12-deoxyphorbol 13-phenylacetate 20-acetate |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.29g/cm3 |
|---|---|
| Boiling Point | 635.7ºC at 760 mmHg |
| Molecular Formula | C30H36O7 |
| Molecular Weight | 508.60300 |
| Flash Point | 204.3ºC |
| Exact Mass | 508.24600 |
| PSA | 110.13000 |
| LogP | 3.32370 |
| Index of Refraction | 1.607 |
| InChIKey | MEDVHSNRBPAIPU-XMOZQXTISA-N |
| SMILES | CC(=O)OCC1=CC2C3C(C)(C)C3(OC(=O)Cc3ccccc3)CC(C)C2(O)C2C=C(C)C(=O)C2(O)C1 |
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H300-H310-H315-H319-H330-H335 |
| Precautionary Statements | P260-P264-P280-P284-P301 + P310-P302 + P350 |
| RIDADR | UN 2811 6.1 / PGIII |
Articles13
More Articles| Phosphorylation of connexin43 and inhibition of gap junctional communication in 12-O-tetradecanoylphorbol-13-acetate-exposed R6 fibroblasts: minor role of protein kinase C beta I and mu. Carcinogenesis 22(2) , 221-31, (2001) 12-O:-tetradecanoylphorbol-13-acetate (TPA) inhibits gap junctional communication in many cell culture systems, but TPA-induced phosphorylation of the gap junction protein connexin43 (Cx43) varies muc... | |
| Protein kinase C modulates insulin action in human skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 278(3) , E553-62, (2000) There is good evidence from cell lines and rodents that elevated protein kinase C (PKC) overexpression/activity causes insulin resistance. Therefore, the present study determined the effects of PKC ac... | |
| Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay. J. Cereb. Blood Flow Metab. 30(9) , 1593-7, (2010) Blood-brain barrier (BBB) P-glycoprotein activity is rapidly reduced by vascular endothelial growth factor (VEGF) acting via Src and by tumor necrosis factor-alpha acting via protein kinase C (PKC)bet... |
Synonyms
| 12-deoxyphorbolphenylacetate-20-acetate |
| 3-acetate9a-phenylacetate |
| 12-DPPAA |
