CAS 119577-28-5|12-Ethyl-9-hydroxycamptothecin

Introduction：Basic information about CAS 119577-28-5|12-Ethyl-9-hydroxycamptothecin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 12-Ethyl-9-hydroxycamptothecin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	12-Ethyl-9-hydroxycamptothecin
CAS Number	119577-28-5	Molecular Weight	392.40
Density	1.5±0.1 g/cm3	Boiling Point	810.3±65.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₀N₂O₅	Melting Point	/
MSDS	/	Flash Point	443.8±34.3 °C

Names

Name	7-ethyl-10-hydroxycamptothecin
Synonym	More Synonyms

12-Ethyl-9-hydroxycamptothecin BiologicalActivity

Description	12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro	12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin.
References	[1]. Luzzio MJ, et al. Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I. J Med Chem. 1995;38(3):395-401.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	810.3±65.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₀N₂O₅
Molecular Weight	392.40
Flash Point	443.8±34.3 °C
Exact Mass	392.137207
PSA	101.65000
LogP	2.31
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.738
Storage condition	2-8C

Safety Information

HS Code	2942000000

Customs

HS Code	2942000000

Synonyms

(4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4,9-dihydroxy-, (4S)-

SN-38

SN38

7-Ethyl-10-hydroxycamptothecine

(4S)-4,11-DIETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7] INDOLIZINO [1,2-B] QUINOLINE-3,14 (4H,12H)-DIONE

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