CAS 1131-94-8|3-Hydroxy-4-methoxyphenylacetic acid

Introduction:Basic information about CAS 1131-94-8|3-Hydroxy-4-methoxyphenylacetic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name3-Hydroxy-4-methoxyphenylacetic acid
CAS Number1131-94-8Molecular Weight182.173
Density1.3±0.1 g/cm3Boiling Point371.3±27.0 °C at 760 mmHg
Molecular FormulaC9H10O4Melting Point128 °C
MSDSChineseUSAFlash Point153.1±17.2 °C
Symbol
GHS07
Signal WordWarning

Names

Nameisohomovanillic acid
SynonymMore Synonyms

3-Hydroxy-4-methoxyphenylacetic acid BiologicalActivity

DescriptionIsohomovanillic acid (3-Hydroxy-4-methoxyphenylacetic acid) is extracted from urine at pH 2 by ethyl acetate. Isohomovanillic acid is not found in appreciable values in many normal human urines[1].
Related CatalogResearch Areas >>Cancer
Target

Human Endogenous Metabolite

References

[1]. Comoy E, et al. Iso-homovanillic acid determination in human urine. Clin Chim Acta. 1971 Dec;35(2):369-75.

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point371.3±27.0 °C at 760 mmHg
Melting Point128 °C
Molecular FormulaC9H10O4
Molecular Weight182.173
Flash Point153.1±17.2 °C
Exact Mass182.057907
PSA66.76000
LogP0.47
Vapour Pressure0.0±0.9 mmHg at 25°C
Index of Refraction1.573
InChIKeyBWXLCOBSWMQCGP-UHFFFAOYSA-N
SMILESCOc1ccc(CC(=O)O)cc1O

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH302-H315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Hazard CodesXi,Xn
Risk Phrases22-36/37/38
Safety Phrases26-36
RIDADRNONH for all modes of transport
HS Code2918990090

Customs

HS Code2918990090
Summary2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles4

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Determination of 4-O-methylated catecholamine metabolites in urine by mass fragmentography.

Clin. Chem. 25(10) , 1708-13, (1979)

We describe the determination of the 4-O-methylated catecholamine metabolites 4-methoxy-3-hydroxyphenylacetic acid (iso-HVA), 4-methoxy-3-hydroxyphenylmandelic acid (iso-VMA) and 4-methoxy-3-hydroxyph...

Levels of dopamine and 3,4-dihydroxyphenylacetic acid in the adenohypophysis of normo- and hypertensive rats.

Clin. Exp. Hypertens. A. 12(3) , 343-53, (1990)

The levels of dopamine and its metabolites in the adenohypophysis of the normo- and hypertensive rats were determined. Dopamine was present as the free and sulfate-conjugated form in the adenohypophys...

Determination of homovanillic, isohomovanillic and vanillylmandelic acids in human urine by means of glass capillary gas-liquid chromatography with temperature-programmed electron-capture detection.

J. Chromatogr. A. 183(4) , 391-401, (1980)

The determination of urinary homovanillic, isohomovanillic and vanillylmandelic acids as their trifluoroacetylhexafluoroisopropyl ester derivatives by glass capillary gas-liquid chromatography has bee...

Synonyms

(3-Hydroxy-4-methoxyphenyl)acetic acid
MFCD00016829
Benzeneacetic acid, 3-hydroxy-4-methoxy-
2-(3-hydroxy-4-methoxyphenyl)acetic acid
3-Hydroxy-4-methoxybenzeneacetic acid
Homoisovanillic acid
QV1R CQ DO1
3-Hydroxy-4-methoxyphenylacetic acid
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