CAS 950-99-2|2H-1-Benzopyran-6-ol,3,4-dihydro-2,2,5,7,8-pentamethyl-

Introduction：Basic information about CAS 950-99-2|2H-1-Benzopyran-6-ol,3,4-dihydro-2,2,5,7,8-pentamethyl-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	2H-1-Benzopyran-6-ol,3,4-dihydro-2,2,5,7,8-pentamethyl-
CAS Number	950-99-2	Molecular Weight	220.30700
Density	1.034g/cm3	Boiling Point	344.3ºC at 760 mmHg
Molecular Formula	C₁₄H₂₀O₂	Melting Point	89-91ºC(lit.)
MSDS	/	Flash Point	146.1ºC

Names

Name	2,2,5,7,8-pentamethyl-3,4-dihydrochromen-6-ol
Synonym	More Synonyms

BiologicalActivity

Description	2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Androgen Receptor
References	[1]. Kyriakopoulos CE, et al. A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer. Invest New Drugs. 2016 Apr;34(2):225-30.

Chemical & Physical Properties

Density	1.034g/cm3
Boiling Point	344.3ºC at 760 mmHg
Melting Point	89-91ºC(lit.)
Molecular Formula	C₁₄H₂₀O₂
Molecular Weight	220.30700
Flash Point	146.1ºC
Exact Mass	220.14600
PSA	29.46000
LogP	3.42100
Index of Refraction	1.529
InChIKey	SEBPXHSZHLFWRL-UHFFFAOYSA-N
SMILES	Cc1c(C)c2c(c(C)c1O)CCC(C)(C)O2

Safety Information

Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26-36
HS Code	2932999099

Customs

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

PMHCR

2H-1-Benzopyran-6-ol,3,4-dihydro-2,2,5,7,8-pentamethyl

2,2,5,7,8-pentamethyl-6-hydroxy-chromane

MFCD00210347

Chromane C1

6-Hydroxy-2,2,5,7,8-pentamethylchroman

2,2,5,7,8-pentamethylchroman-6-ol

2,2,5,7,8-Pentamethyl-1-hydroxychroman

2,2,5,7,8-Pentamethyl-6-hydroxychroman

2,2,5,7,8-Pentamethyl-6-chromanol

Chroman C1

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