Introduction：Basic information about CAS 19908-48-6|Maackiain, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Maackiain |
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| CAS Number | 19908-48-6 | Molecular Weight | 284.263 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 436.2±45.0 °C at 760 mmHg |
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| Molecular Formula | C16H12O5 | Melting Point | / |
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| MSDS | / | Flash Point | 217.6±28.7 °C |
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Names
| Name | (+)-Maackiain |
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| Synonym | More Synonyms |
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Maackiain BiologicalActivity
| Description | Maackiain (DL-Maackiain) is isolated from Maackia amurensis Rupr.et Maxim. Maackiain (DL-Maackiain) is a larvicidal agent against Aedes aegypti mosquito.xp Parasitol with a LD50 of 21.95 µg/mL[1]. Maackiain (DL-Maackiain) induces fragmentations of DNA to oligonucleosomal-sized fragments that like a characteristic of apoptosis in the HL-60 cells[2]. |
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| Related Catalog | Research Areas >>Infection |
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| Target | LD50: 21.95 µg/mL (Aedes aegypti mosquito.xp Parasitol)[1] |
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| References | [1]. Bezerra-Silva PC, et al. Extract of Bowdichia virgilioides and maackiain as larvicidal agent against Aedes aegypti mosquito.xp Parasitol. 2015 Jun;153:160-4. [2]. Aratanechemuge Y, et al. Induction of apoptosis by maackiain and trifolirhizin (maackiain glycoside) isolated from sanzukon (Sophora Subprostrate Chen et T. Chen) in human promyelotic leukemia HL-60 cells.Oncol Rep. 2004 Dec;12(6):1183-8. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 436.2±45.0 °C at 760 mmHg |
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| Molecular Formula | C16H12O5 |
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| Molecular Weight | 284.263 |
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| Flash Point | 217.6±28.7 °C |
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| Exact Mass | 284.068481 |
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| PSA | 57.15000 |
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| LogP | 2.79 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.677 |
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| InChIKey | HUKSJTUUSUGIDC-UHFFFAOYSA-N |
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| SMILES | Oc1ccc2c(c1)OCC1c3cc4c(cc3OC21)OCO4 |
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| Storage condition | 2-8C |
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Synonyms
| rac-maackiain |
| 6a,12a-Dihydro-6H-[1,3]dioxolo[5,6][1]benzofuro[3,2-c]chromen-3-ol |
| 6a,12a-Dihydro-6H-[1,3]dioxolo[4',5':5,6][1]benzofuro[3,2-c]chromen-3-ol |
| 4-Chlorobenzamideoxime |
| maackiain |
| 6H-(1,3)Dioxolo(5,6)benzofuro(3,2-c)(1)benzopyran-3-ol, 6a,12a-dihydro-, (6aR-cis)- |
| (6aR,12aR)-6a,12a-Dihydro-6H-[1,3]dioxolo[5,6][1]benzofuro[3,2-c]chromen-3-ol |
| 6a,12a-Dihydro-6H-(1,3)dioxolo(5,6)benzofuro(3,2-c)chromen-3-ol |
| 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-3-ol, 6a,12a-dihydro- |
| demethylpterocarpin |
| 6a,12a-Dihydro-6H-(1,3)dioxolo(5,6)benzofuro(3,2-c)(1)benzopyran-3-ol |
| 6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-3-ol, 6a,12a-dihydro-, (6aR,12aR)- |
| (±)-Maackiain |
| dl-Maackiain |
