Introduction：Basic information about CAS 436-32-8|Diffractaic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Diffractaic acid |
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| CAS Number | 436-32-8 | Molecular Weight | 374.38400 |
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| Density | 1.26g/cm3 | Boiling Point | 604.9ºC at 760mmHg |
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| Molecular Formula | C20H22O7 | Melting Point | / |
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| MSDS | / | Flash Point | 214.2ºC |
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Names
| Name | 4-(2,4-dimethoxy-3,6-dimethylbenzoyl)oxy-2-hydroxy-3,6-dimethylbenzoic acid |
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| Synonym | More Synonyms |
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Diffractaic acid BiologicalActivity
| Description | Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research[1]. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta[2]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerResearch Areas >>Inflammation/Immunology |
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| In Vivo | Diffractaic acid shows an analgesic effect by Acetic acid-induced writhing and tail-pressure methods in mice[2]. |
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| References | [1]. Fehmi Odabasoglu, et al. Diffractaic acid, a novel proapoptotic agent, induces with olive oil both apoptosis and antioxidative systems in Ti-implanted rabbits. Eur J Pharmacol. 2012 Jan 15;674(2-3):171-8. [2]. E Okuyama, et al. Usnic acid and diffractaic acid as analgesic and antipyretic components of Usnea diffracta. Planta Med. 1995 Apr;61(2):113-5. |
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Chemical & Physical Properties
| Density | 1.26g/cm3 |
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| Boiling Point | 604.9ºC at 760mmHg |
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| Molecular Formula | C20H22O7 |
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| Molecular Weight | 374.38400 |
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| Flash Point | 214.2ºC |
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| Exact Mass | 374.13700 |
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| PSA | 102.29000 |
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| LogP | 3.56040 |
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| Vapour Pressure | 1.74E-15mmHg at 25°C |
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| Index of Refraction | 1.583 |
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| InChIKey | MIJKZXWOOXIEEU-UHFFFAOYSA-N |
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| SMILES | COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)O)c(O)c2C)c(OC)c1C |
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| Storage condition | 2-8℃ |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- VH3708850
- CHEMICAL NAME :
- beta-Resorcylic acid, 3,6-dimethyl-, 4-(2,4-dimethoxy-3,6-dimethylbenzoate)
- CAS REGISTRY NUMBER :
- 436-32-8
- BEILSTEIN REFERENCE NO. :
- 2915070
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C20-H22-O7
- MOLECULAR WEIGHT :
- 374.42
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 962 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,335,1981
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Safety Information
Customs
| HS Code | 2918990090 |
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| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 2,4-dimethoxy-3,6-dimethylbenzoic acid 4'-carboxy-3'-hydroxy-2',5'-dimethylphenyl ester |
| diffractic acid |
| diffractaic acid |
| Diffractasaeure |
| Dirbizomic acid |
| DIFFRACTOIC ACID |
| Dirhizomic acid |
| DIFFRACTANIC ACID |
| diffratic acid |
