CAS 4093-35-0|Bromopride

Introduction：Basic information about CAS 4093-35-0|Bromopride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Bromopride BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Synonyms

Common Name	Bromopride
CAS Number	4093-35-0	Molecular Weight	344.247
Density	1.3±0.1 g/cm3	Boiling Point	435.8±45.0 °C at 760 mmHg
Molecular Formula	C₁₄H₂₂BrN₃O₂	Melting Point	148-150ºC
MSDS	/	Flash Point	217.3±28.7 °C

Names

Name	4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
Synonym	More Synonyms

Bromopride BiologicalActivity

Description	Bromopride is a dopamine antagonist with prokinetic properties， widely used as an antiemetic.
Related Catalog	Signaling Pathways >>GPCR/G Protein >>Dopamine ReceptorSignaling Pathways >>Neuronal Signaling >>Dopamine ReceptorResearch Areas >>Neurological Disease

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	435.8±45.0 °C at 760 mmHg
Melting Point	148-150ºC
Molecular Formula	C₁₄H₂₂BrN₃O₂
Molecular Weight	344.247
Flash Point	217.3±28.7 °C
Exact Mass	343.089539
PSA	67.59000
LogP	2.67
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.565
InChIKey	GIYAQDDTCWHPPL-UHFFFAOYSA-N
SMILES	CCN(CC)CCNC(=O)c1cc(Br)c(N)cc1OC
Storage condition	2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ3280000

CHEMICAL NAME :: o-Anisamide, 4-amino-5-bromo-N-(2-(diethylamino)ethyl)-

CAS REGISTRY NUMBER :: 4093-35-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C14-H22-Br-N3-O2

MOLECULAR WEIGHT :: 344.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 545 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 310 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 105 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,516,1979 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 2520 mg/kg

SEX/DURATION :: lactating female 21 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral

REFERENCE :: PHBHA4 Physiology and Behavior. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1966- Volume(issue)/page/year: 45,1081,1989

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 1320 mg/kg

SEX/DURATION :: female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

REFERENCE :: PHBHA4 Physiology and Behavior. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1966- Volume(issue)/page/year: 45,1081,1989

Safety Information

Hazard Codes	Xn: Harmful;
Risk Phrases	20/21/22
Safety Phrases	36
WGK Germany	3
RTECS	BZ3280000
HS Code	2924299090

Customs

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide

Artomey

Valopride

4-amino-5-bromo-N-(2-diethylaminoethyl)-2-anisamide

Viaben

4-amino-5-bromo-N-(2-diethylaminoethyl)-2-methoxybenzamide

Viadil

Digesan

Plamet

4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-o-anisamide

Benzamide, 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxy-

Bromoprida [INN-Spanish]

Bromopridum [INN-Latin]

Emepride

Bromopride

Emoril

Bromoprida [Spanish]

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