Introduction：Basic information about CAS 148067-21-4|Calcineurin autoinhibitory peptide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Calcineurin autoinhibitory peptide |
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| CAS Number | 148067-21-4 | Molecular Weight | 2930.32000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C124H205N39O39S2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Calcineurin autoinhibitory fragment |
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| Synonym | More Synonyms |
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Calcineurin autoinhibitory peptide BiologicalActivity
| Description | Calcineurin autoinhibitory peptide is a selective inhibitor of Ca2+/calmodulin-dependent protein phosphatase (calcineurin), with an IC50 of ~10 μM. Calcineurin autoinhibitory peptide could protect neurons from excitatory neuronal death[1][2]. |
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| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>PhosphataseResearch Areas >>Neurological Disease |
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| Target | IC50: ~10 μM (calcineurin)[1] |
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| References | [1]. Hashimoto Y, et, al. Identification of an autoinhibitory domain in calcineurin. J Biol Chem. 1990 Feb 5; 265(4): 1924-7. [2]. Terada H, et, al. Inhibition of excitatory neuronal cell death by cell-permeable calcineurin autoinhibitory peptide. J Neurochem. 2003 Dec; 87(5): 1145-51. |
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Chemical & Physical Properties
| Molecular Formula | C124H205N39O39S2 |
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| Molecular Weight | 2930.32000 |
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| Exact Mass | 2928.47000 |
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| PSA | 1329.62000 |
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| LogP | 1.97210 |
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| Storage condition | -20°C |
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Safety Information
| Hazard Codes | Xi |
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| WGK Germany | 3.0 |
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Synonyms
| ITSFEEAKGLDRINERMPPRRDAMP |
| Calcineurin autoinhibitory peptide |
