CAS 118-82-1|4,4'-Methylenebis(2,6-di-tert-butylphenol)

Introduction：Basic information about CAS 118-82-1|4,4'-Methylenebis(2,6-di-tert-butylphenol), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	4,4'-Methylenebis(2,6-di-tert-butylphenol)
CAS Number	118-82-1	Molecular Weight	424.659
Density	1.0±0.1 g/cm3	Boiling Point	459.5±40.0 °C at 760 mmHg
Molecular Formula	C₂₉H₄₄O₂	Melting Point	155-159 °C(lit.)
MSDS	ChineseUSA	Flash Point	178.1±21.9 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	4,4'-Methylenebis(2,6-di-tert-butylphenol)
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	459.5±40.0 °C at 760 mmHg
Melting Point	155-159 °C(lit.)
Molecular Formula	C₂₉H₄₄O₂
Molecular Weight	424.659
Flash Point	178.1±21.9 °C
Exact Mass	424.334137
PSA	40.46000
LogP	9.49
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.527
InChIKey	MDWVSAYEQPLWMX-UHFFFAOYSA-N
SMILES	CC(C)(C)c1cc(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL9650000

CHEMICAL NAME :: Phenol, 4,4'-methylenebis(2,6-bis(1,1-dimethylethyl)-

CAS REGISTRY NUMBER :: 118-82-1

BEILSTEIN REFERENCE NO. :: 1916919

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C29-H44-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2021 mg/kg/1W-C

TOXIC EFFECTS :: Liver - other changes Blood - other changes Biochemical - Metabolism (Intermediary) - lipids including transport

REFERENCE :: TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 8,77,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 56700 mg/kg/2Y-C

TOXIC EFFECTS :: Gastrointestinal - ulceration or bleeding from large intestine Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring) Related to Chronic Data - death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536073 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83032 No. of Facilities: 7725 (estimated) No. of Industries: 96 No. of Occupations: 64 No. of Employees: 120009 (estimated) No. of Female Employees: 20306 (estimated)

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	SL9650000
HS Code	2907299090

Customs

HS Code	2907299090
Summary	2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

Articles1

Effects of four bisphenolic antioxidants on lipid contents of rat liver.

Toxicol. Lett. 8(1-2) , 77-86, (1981)

Hepatic lipids were studied in Sprague-Dawley male rats given, 2,2'-methylenebis(4-ethyl-6-tert-butylphenol), 2,2'-methylenebis(4-methyl-6-tert-butylphenol), 4,4'-butylidenebis(3-methyl-6-tert-butylph...

Synonyms

Bis(3,5-di-tert-butyl-4-hydroxyphenyl)methane

4,4'-Methylenebis[2,6-bis(2-methyl-2-propanyl)phenol]

4,4'-methanediylbis(2,6-di-tert-butylphenol)

MFCD00008822

Phenol, 4,4'-methylenebis[2,6-bis(1,1-dimethylethyl)-

Ethanox 702

3,3',5,5'-Tetra-tert-butyl-4,4'-dihydroxydiphenylmethane

Phenol, 4,4'-methylenebis[2,6-di-tert-butyl-

4,4'-Methylenebis(2,6-di-tert-butylphenol)

EINECS 204-279-1

2,6-ditert-butyl-4-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]phenol

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