Introduction：Basic information about CAS 14919-49-4|3,4'-Dihydroxyflavone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3,4'-Dihydroxyflavone |
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| CAS Number | 14919-49-4 | Molecular Weight | 254.24 |
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| Density | 1.472g/cm3 | Boiling Point | 452.5ºC at 760mmHg |
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| Molecular Formula | C15H10O4 | Melting Point | 275-276ºC |
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| MSDS | / | Flash Point | 175.7ºC |
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Names
| Name | 3-hydroxy-2-(4-hydroxyphenyl)chromen-4-one |
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| Synonym | More Synonyms |
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3,4'-Dihydroxyflavone BiologicalActivity
| Description | 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1]. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>Infection |
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| In Vivo | 3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1]. Animal Model: 3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1]. Dosage: 1 mg/kg per 30 μL. Administration: Oral administration daily for 5 days. Result: Significantly decreased virus titers and pathological changes in the lung and reduced body weight loss and death. |
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| References | [1]. Hossain MK, et al. Antiviral activity of 3,4'-dihydroxyflavone on influenza a virus. J Microbiol. 2014 Jun;52(6):521-6. |
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Chemical & Physical Properties
| Density | 1.472g/cm3 |
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| Boiling Point | 452.5ºC at 760mmHg |
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| Melting Point | 275-276ºC |
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| Molecular Formula | C15H10O4 |
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| Molecular Weight | 254.24 |
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| Flash Point | 175.7ºC |
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| Exact Mass | 254.05800 |
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| PSA | 70.67000 |
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| LogP | 2.87120 |
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| Vapour Pressure | 5.61E-09mmHg at 25°C |
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| Index of Refraction | 1.712 |
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| InChIKey | GPGOCTLAUAHUQO-UHFFFAOYSA-N |
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| SMILES | O=c1c(O)c(-c2ccc(O)cc2)oc2ccccc12 |
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Safety Information
Customs
| HS Code | 2914501900 |
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| Summary | 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
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Synonyms
| 3-Hydroxy-2-(4-hydroxyphenyl)chromone |
| 4'-Hydroxyflavonol |
| 3-hydroxy-2-(4-hydroxy-phenyl)-chromen-4-one |
| 3,4'-dihydroxyfavone |
| 3-Hydroxy-2-(4-hydroxy-phenyl)-chromen-4-on |
| 3,4'-dihydroxyfalvone |
| 3,4'-Dihydroxyflavone |
