Introduction：Basic information about CAS 2179-37-5|Benzcyclane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Benzcyclane |
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| CAS Number | 2179-37-5 | Molecular Weight | 289.45600 |
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| Density | 0.97g/cm3 | Boiling Point | 384.2ºC at 760mmHg |
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| Molecular Formula | C19H31NO | Melting Point | / |
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| MSDS | / | Flash Point | 113.2ºC |
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Names
| Name | 3-(1-benzylcycloheptyl)oxy-N,N-dimethylpropan-1-amine |
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| Synonym | More Synonyms |
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Benzcyclane BiologicalActivity
| Description | Benzcyclane (Bencyclane; Benzcyclan) is a platelet aggregation inhibitor and a vasodilator effective in a variety of peripheral circulation disorders. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Cardiovascular Disease |
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| In Vivo | Benzcyclane, although capable of aggregating platelets by itself at very high concentrations, shows a striking inhibitory effect, over a wide range of concentrations, both on platelet aggregation induced by ADP, epinephrine or collagen and on platelet adhesiveness to glass or collagen. Clot retraction is also clearly inhibited[1]. Benzcyclane induces use-dependent inhibition of Na channels in muscle, similarly as do class 1 antiarrhytnmic drugs. Inhibition was observed with both normal and cevadine-modified Na channels[2]. |
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| References | [1]. Ponari O, et al. In vitro effects of bencyclan on coagulation, fibrinolysis and platelet function. Arzneimittelforschung. 1976;26(8):1532-8. [2]. Nánási PP, et al. Effects of bencyclane on normal and cevadine-modified Na channels in frog skeletal muscle. Gen Physiol Biophys. 1989 Oct;8(5):447-58. |
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Chemical & Physical Properties
| Density | 0.97g/cm3 |
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| Boiling Point | 384.2ºC at 760mmHg |
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| Molecular Formula | C19H31NO |
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| Molecular Weight | 289.45600 |
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| Flash Point | 113.2ºC |
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| Exact Mass | 289.24100 |
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| PSA | 12.47000 |
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| LogP | 4.29040 |
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| Vapour Pressure | 4.17E-06mmHg at 25°C |
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| Index of Refraction | 1.52 |
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| InChIKey | FYJJXENSONZJRG-UHFFFAOYSA-N |
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| SMILES | CN(C)CCCOC1(Cc2ccccc2)CCCCCC1 |
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| Storage condition | 2-8℃ |
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Safety Information
Customs
| HS Code | 2922199090 |
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| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Benzcyclan |
| EINECS 218-547-0 |
| BENCYCLANE |
| Benzcyclane |
