Introduction：Basic information about CAS 120638-55-3|bromfenac sodium salt sesquihydrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | bromfenac sodium salt sesquihydrate |
|---|
| CAS Number | 120638-55-3 | Molecular Weight | 383.17 |
|---|
| Density | 1.6±0.1 g/cm3 | Boiling Point | 562.2±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C15H12BrNO3.3/2H2O.Na | Melting Point | / |
|---|
| MSDS | / | Flash Point | 293.8±30.1 °C |
|---|
Names
| Name | bromfenac sodium salt sesquihydrate |
|---|
| Synonym | More Synonyms |
|---|
bromfenac sodium salt sesquihydrate BiologicalActivity
| Description | Bromfenac (sodium hydrate) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity(1) Bromfenac (sodium hydrate) (1 mg/kg, i.v.) is metabolited into an unusual conjugate, bromfenac N-glucoside, in rats bile(2) Bromfenac (sodium hydrate) permeation was found to be 1.62-fold higher through ChS-CS-NPs |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
|---|
| References | [1]. Kirkman SK et al. Isolation and identification of bromfenac glucoside from rat bile. Drug Metab Dispos. 1998 Jul;26(7):720-3. [2]. Abdullah TA et al. Chondroitin sulfate-chitosan nanoparticles for ocular delivery of bromfenac sodium: Improved permeation, retention, and penetration. Int J Pharm Investig. 2016 Apr-Jun;6(2):96-105. |
|---|
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|
| Boiling Point | 562.2±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C15H12BrNO3.3/2H2O.Na |
|---|
| Molecular Weight | 383.17 |
|---|
| Flash Point | 293.8±30.1 °C |
|---|
| PSA | 80.39000 |
|---|
| LogP | 2.72 |
|---|
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
|---|
| Index of Refraction | 1.663 |
|---|
| InChIKey | PPOSVVJOVKVBPW-UHFFFAOYSA-L |
|---|
| SMILES | Nc1c(CC(=O)[O-])cccc1C(=O)c1ccc(Br)cc1.Nc1c(CC(=O)[O-])cccc1C(=O)c1ccc(Br)cc1.O.O.O.[Na+].[Na+] |
|---|
| Storage condition | 2-8℃ |
|---|
Synonyms
| Sodium (2-amino-3-(4-bromobenzoyl)phenyl)acetate |
| bromfenacum [INN_la] |
| Bromfenac monosodium salt sesquihydrate |
| Unii-8ecv571Y37 |
| [2-Amino-3-(4-bromobenzoyl)phenyl]acetic acid |
| BroMfenac sodiuM 1.5H2O |
| Bromfenac Sodium Sesquihydrate |
| Bromfenac ophthalmic |
| Bromfenac ophthalmic solution |
| Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)- |
| bromfenac |
| Bromfenac sodium |
| Duract |
| Bromfenac (sodium hydrate) |
