CAS 128470-15-5|Melarsomine

Introduction：Basic information about CAS 128470-15-5|Melarsomine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Melarsomine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Melarsomine
CAS Number	128470-15-5	Molecular Weight	428.41100
Density	/	Boiling Point	678.1ºC at 760mmHg
Molecular Formula	C₁₃H₂₁AsN₈S₂	Melting Point	/
MSDS	/	Flash Point	363.9ºC

Names

Name	2-N-[4-[bis(2-aminoethylsulfanyl)arsanyl]phenyl]-1,3,5-triazine-2,4,6-triamine
Synonym	More Synonyms

Melarsomine BiologicalActivity

Description	Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections[1][2].
Related Catalog	Research Areas >>Infection
In Vivo	Melarsomine (2.5 mg/kg; deep i.m. injection) combined with Doramectin managed to clear the D. repens infection in dogs[1]. Melarsomine (0.25 mg/kg; deep i.m. injection) can cure T. evansi infection in camels[2]. Melarsomine (0.5 mg/kg; deep i.m. injection) can cure T. evansi infection in dairy cattle in Thailand[2].
References	[1]. Baneth G, et, al. Dirofilaria repens infection in a dog: diagnosis and treatment with melarsomine and doramectin. Vet Parasitol. 2002 Apr 30;105(2):173-8. [2]. Desquesnes M, et, al. An evaluation of melarsomine hydrochloride efficacy for parasitological cure in experimental infection of dairy cattle with Trypanosoma evansi in Thailand. Parasitology. 2011 Aug;138(9):1134-42.

Chemical & Physical Properties

Boiling Point	678.1ºC at 760mmHg
Molecular Formula	C₁₃H₂₁AsN₈S₂
Molecular Weight	428.41100
Flash Point	363.9ºC
Exact Mass	428.05500
PSA	205.38000
LogP	2.49460
Vapour Pressure	3.03E-18mmHg at 25°C
InChIKey	MGEOLZFMLHYCFZ-UHFFFAOYSA-N
SMILES	NCCS[As](SCCN)c1ccc(Nc2nc(N)nc(N)n2)cc1

Synonyms

Melarsomine

Melarsominum [INN-Latin]

Melarsomina

Melarsomina [INN-Spanish]

Bis(2-aminoethyl) p-((4,6-diamino-s-triazin-2-yl)amino)dithiobenzenearsonite

Melarsomine (INN)

Melarsominum

UNII-374GJ0S41A

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