Introduction：Basic information about CAS 15387-10-7|N-[[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-propan-2-ylamino]methyl]pyridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-[[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-propan-2-ylamino]methyl]pyridine-3-carboxamide |
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| CAS Number | 15387-10-7 | Molecular Weight | 379.45600 |
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| Density | 1.25g/cm3 | Boiling Point | / |
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| Molecular Formula | C21H25N5O2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | N-[[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-propan-2-ylamino]methyl]pyridine-3-carboxamide |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.25g/cm3 |
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| Molecular Formula | C21H25N5O2 |
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| Molecular Weight | 379.45600 |
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| Exact Mass | 379.20100 |
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| PSA | 72.16000 |
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| LogP | 2.87260 |
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| Index of Refraction | 1.638 |
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| InChIKey | MZQAQBDIKUFBSF-UHFFFAOYSA-N |
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| SMILES | Cc1c(N(CNC(=O)c2cccnc2)C(C)C)c(=O)n(-c2ccccc2)n1C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- QS4025000
- CHEMICAL NAME :
- Nicotinamide, N-((antipyrinylisopropylamino)methyl)-
- CAS REGISTRY NUMBER :
- 15387-10-7
- BEILSTEIN REFERENCE NO. :
- 0766712
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C21-H25-N5-O2
- MOLECULAR WEIGHT :
- 379.51
- WISWESSER LINE NOTATION :
- T6NJ CVM1NY1&1&- DT5NNVJ A1 BR& E1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1460 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1060 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 853 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970
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Synonyms
| Ra 101 (pharmaceutical) |
| Niprofazonum [INN-Latin] |
| 1-Phenyl-2,3-dimethyl-4(N-nicotinamidomethyl-N-isopropyl)amino-5-pyrazolone |
| Nicotinamide,N-((antipyrinylisopropylamino)methyl) |
| Nicotinamidomethylaminopyrazolone |
| Niprofazona [INN-Spanish] |
| Niprofazone |
| RA 101 |
| N-{[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-isopropyl-amino]-methyl}-nicotinamide |
| N-((Antipyrinylisopropylamino)methyl)nicotinamide |
