CAS 574-92-5|4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid

Introduction：Basic information about CAS 574-92-5|4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Articles1
6. Synonyms

Common Name	4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid
CAS Number	574-92-5	Molecular Weight	257.16500
Density	1.55 g/cm3	Boiling Point	354.7ºC at 760 mmHg
Molecular Formula	C₁₁H₆F₃NO₃	Melting Point	259-260 °C (dec.)(lit.)
MSDS	ChineseUSA	Flash Point	168.3ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	4-hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.55 g/cm3
Boiling Point	354.7ºC at 760 mmHg
Melting Point	259-260 °C (dec.)(lit.)
Molecular Formula	C₁₁H₆F₃NO₃
Molecular Weight	257.16500
Flash Point	168.3ºC
Exact Mass	257.03000
PSA	70.42000
LogP	2.65740

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VB2188000

CHEMICAL NAME :: 3-Quinolinecarboxylic acid, 4-hydroxy-7-(trifluoromethyl)-

CAS REGISTRY NUMBER :: 574-92-5

BEILSTEIN REFERENCE NO. :: 0249406

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H6-F3-N-O3

MOLECULAR WEIGHT :: 257.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977- Volume(issue)/page/year: 9,585,1983

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	VB2188000

Articles1

Synthesis and testing of new antileukemic Schiff bases of N-hydroxy-N'-aminoguanidine against CCRF-CEM/0 human leukemia cells in vitro and synergism studies with cytarabine (Ara-C).

Pharm. Res. 10(4) , 515-20, (1993)

A series of eight new N-hydroxy-N'-aminoguanidine (HAG) Schiff bases [ArCH = NNHC(= NH)NHOH.tosylate] was synthesized as potential antitumor agents through the inhibition of the enzyme ribonucleotide ...

Synonyms

MFCD00006771

4-hydroxy-7-trifluoromethyl-3-quinoline-carboxylic acid

EINECS 209-377-8

4-Hydroxy-7-trifluoromethyl-3-quinolinecarboxylic acid,HPLC

4-HYDROXY-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLIC ACID

4-hydroxy-7-(trifluoromethyl)-3-quinolinecarboxylicaci

4-Hydroxy-7-trifluormethyl-chinolin-3-carbonsaeure

3-Carboxy-4-hydroxy-7-trifluoromethylquinoline.

7-trifluoromethyl-4-hydroxyquinoline-3-carboxylic acid

BUTTPARK 219-48

4-HYDROXY-7-TRIFLUOROMETHYL-3-QUINOLINE-CARBOXYLIC ACID,TECH.

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