CAS 142846-71-7|M35

Introduction：Basic information about CAS 142846-71-7|M35, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. M35 BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	M35
CAS Number	142846-71-7	Molecular Weight	2233.60
Density	/	Boiling Point	/
Molecular Formula	C₁₀₇H₁₅₃N₂₇O₂₆	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	M35 Peptide
Synonym	More Synonyms

M35 BiologicalActivity

Description	Galanin Receptor Ligand M35 is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic islets. Galanin Receptor Ligand M35 exerts a Ki values of 0.11 and 2.0 nM for human GalR1 and GalR2, respectively[1][2].
Related Catalog	Research Areas >>Neurological DiseaseSignaling Pathways >>GPCR/G Protein >>Neuropeptide Y Receptor
Target	Ki: 0.11 nM (GalR1), 2.0 nM (GalR2)[2]
References	[1]. Kask K, et al. Binding and agonist/antagonist actions of M35, galanin(1-13)-bradykinin(2-9)amide chimeric peptide, in Rin m 5F insulinoma cells. Regul Pept. 1995 Nov 10;59(3):341-8. [2]. Webling KE, et al. Galanin receptors and ligands. Front Endocrinol (Lausanne). 2012 Dec 7;3:146.

Chemical & Physical Properties

Molecular Formula	C₁₀₇H₁₅₃N₂₇O₂₆
Molecular Weight	2233.60
Exact Mass	2232.15000
PSA	817.65000
LogP	2.16320
InChIKey	JWMXJVFGTXYBFM-UHFFFAOYSA-N
SMILES	CC(C)CC(NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CN)C(C)O)C(=O)NCC(=O)N1CCCC1C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NC(CO)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(=N)N)C(N)=O

Safety Information

Safety Phrases	22-24/25

Synonyms

GWTLNSAGYLLGPPPGFSPFR-CONH2

L-Argininamide,glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl

M 35

Galanin-(1-13)-bradykinin-(2-9)-amide

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