CAS 59-02-9|DL-alpha-Tocopherol

[1]. Geissler RG, et al. In vitro improvement of bone marrow-derived hematopoietic colony formation in HIV-positive patients by alpha-D-tocopherol and erythropoietin. Eur J Haematol. 1994 Oct;53(4):201-6.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

DJ2900000

CHEMICAL NAME :

2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltr idecyl)-, (2R-(2R*(4R*,8R*)))-

CAS REGISTRY NUMBER :

59-02-9

LAST UPDATED :

199701

DATA ITEMS CITED :

5

MOLECULAR FORMULA :

C29-H50-O2

MOLECULAR WEIGHT :

430.79

WISWESSER LINE NOTATION :

T66 BOT&J C3Y1&3Y1&3Y1&1 C1 G1 HQ I1 J1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

7500 mg/kg

SEX/DURATION :

female 1-20 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - other measures of fertility

TYPE OF TEST :

DNA adduct

MUTATION DATA

TYPE OF TEST :

DNA inhibition

TEST SYSTEM :

Rodent - rat Liver

DOSE/DURATION :

100 umol/L

REFERENCE :

CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 45,337,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5582 No. of Facilities: 279 (estimated) No. of Industries: 4 No. of Occupations: 8 No. of Employees: 6957 (estimated) No. of Female Employees: 3599 (estimated)

Pharm. Dev. Technol. 20(2) , 169-75, (2015)

The main objective of the present study was to develop formulations of noscapine hydrochloride hydrate with enhanced solubility and bioavailability using co-solvent- and cyclodextrin-based approaches....

Pharm. Biol. 53(3) , 386-94, (2015)

Currently, there is a great tendency in cosmetic area to use natural extracts. Coffee silverskin (CS) is the most abundant solid by-product generated during roasting of coffee processing.To evaluate d...

J. Anim. Sci. 93 , 3018-33, (2015)

A total of 240 Holstein bulls (121 ± 2.0 kg initial BW; 99 ± 1.0 d of age), from 2 consecutive fattening cycles, were randomly allocated in 1 of 6 pens and assigned to 1 of the 3 treatments consisting...