CAS 559-70-6|beta-Amyrin
| Common Name | beta-Amyrin | ||
|---|---|---|---|
| CAS Number | 559-70-6 | Molecular Weight | 426.717 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 490.7±44.0 °C at 760 mmHg |
| Molecular Formula | C30H50O | Melting Point | 187-190°C |
| MSDS | ChineseUSA | Flash Point | 217.7±20.7 °C |
Names
| Name | β-amyrin |
|---|---|
| Synonym | More Synonyms |
beta-Amyrin BiologicalActivity
| Description | β-Amyrin, an ingredient of the surface wax of tomato fruit and dandelion coffee, blocks amyloid β (Aβ)-induced long-term potentiation (LTP) impairment. β-amyrin is a promising candidate of treatment for AD[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>Others |
| References | [1]. Park HJ, et al. β-Amyrin Ameliorates Alzheimer's Disease-Like Aberrant Synaptic Plasticity in the Mouse Hippocampus. Biomol Ther (Seoul). 2019 Jul 30. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 490.7±44.0 °C at 760 mmHg |
| Melting Point | 187-190°C |
| Molecular Formula | C30H50O |
| Molecular Weight | 426.717 |
| Flash Point | 217.7±20.7 °C |
| Exact Mass | 426.386169 |
| PSA | 20.23000 |
| LogP | 11.06 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.539 |
| InChIKey | JFSHUTJDVKUMTJ-QHPUVITPSA-N |
| SMILES | CC1(C)CCC2(C)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1 |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R22 |
| Safety Phrases | S22-S45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles34
More Articles| β-Amyrin biosynthesis: the critical role of steric volume at C-19 of 2,3-oxidosqualene for its correct folding to generate the pentacyclic scaffold. Org. Lett. 16(13) , 3548-51, (2014) The effect of the steric volume at C-19 of (3S)-2,3-oxidosqualene 1 on the polycyclization reaction by β-amyrin synthase was examined. The substrate analogs, in which the methyl group at C-19 of 1 was... | |
| Comparative analysis of CYP93E proteins for improved microbial synthesis of plant triterpenoids. Phytochemistry 108 , 47-56, (2014) Cytochrome P450-dependent monooxygenases (P450s) belonging to the CYP93E subfamily catalyze the C-24 oxidation of the triterpene backbone during the biosynthesis of triterpenoid saponins, which are bi... | |
| Antitrypanosomal triterpenoid with an ε-lactone E-ring from Salvia urmiensis. J. Nat. Prod. 76(9) , 1806-9, (2013) A new triterpenoid, urmiensolide (1), was isolated from Salvia urmiensis. The structure was elucidated by a combination of 1D and 2D NMR, HRESIMS, and X-ray crystallographic analyses. The absolute con... |
Synonyms
| B-AMYRIN |
| MFCD00017381 |
| (3β)-Olean-12-én-3-ol |
| Olean-12-en-3-ol |
| (3S,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-Octaméthyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-3-picénol |
| (3β)-Olean-12-en-3-ol |
| β-Amyrenol |
| β-amyrin |
| Olean-12-en-3b-ol |
| AMYRIN,B |
| Olean-12-en-3-ol, (3β)- |
| (3S,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-Octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-3-picenol |
| beta-amyrin |
| b-amyrenol |
| Olean-12-en-3β-ol |
| Einecs 209-204-6 |
