CAS 14008-53-8|3-BROMOTETRAHYDROTHIOPHENE-1,1-DIOXIDE

Introduction：Basic information about CAS 14008-53-8|3-BROMOTETRAHYDROTHIOPHENE-1,1-DIOXIDE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Synonyms

Common Name	3-BROMOTETRAHYDROTHIOPHENE-1,1-DIOXIDE
CAS Number	14008-53-8	Molecular Weight	199.06600
Density	1.815g/cm3	Boiling Point	355.3ºC at 760 mmHg
Molecular Formula	C₄H₇BrO₂S	Melting Point	/
MSDS	/	Flash Point	168.7ºC

Names

Name	3-bromothiolane 1,1-dioxide
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.815g/cm3
Boiling Point	355.3ºC at 760 mmHg
Molecular Formula	C₄H₇BrO₂S
Molecular Weight	199.06600
Flash Point	168.7ºC
Exact Mass	197.93500
PSA	42.52000
LogP	1.64920
Vapour Pressure	6.45E-05mmHg at 25°C
Index of Refraction	1.552
InChIKey	IPOKQKBJDASROB-UHFFFAOYSA-N
SMILES	O=S1(=O)CCC(Br)C1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XN0400000

CHEMICAL NAME :: Thiophene, tetrahydro-3-bromo-, 1,1-dioxide

CAS REGISTRY NUMBER :: 14008-53-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C4-H7-Br-O2-S

MOLECULAR WEIGHT :: 199.08

WISWESSER LINE NOTATION :: T5SWTJ CE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 215 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 119,423,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 44 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 119,423,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 121 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 119,423,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 59 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 119,423,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 119,423,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 29 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 119,423,1959

Safety Information

HS Code	2934999090

Customs

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

3-bromothiolane-1,1-dione

Tetrahydro-3-bromothiophene 1,1-dioxide

Thiophene,tetrahydro-3-bromo-,1,1-dioxide

3-Bromosulfolane

3-Bromotetrahydrothiophene 1,1-dioxide

Bromosulfolane

3-Brom-tetrahydrothiophen-1.1-dioxid

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