Introduction：Basic information about CAS 6714-29-0|1H-Imidazo[1,2-b]pyrazole,2,3-dihydro-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1H-Imidazo[1,2-b]pyrazole,2,3-dihydro- |
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| CAS Number | 6714-29-0 | Molecular Weight | 109.12900 |
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| Density | 1.439g/cm3 | Boiling Point | 267.984ºC at 760 mmHg |
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| Molecular Formula | C5H7N3 | Melting Point | / |
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| MSDS | / | Flash Point | 115.873ºC |
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Names
| Name | 3,5-dihydro-2H-imidazo[1,2-b]pyrazole |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.439g/cm3 |
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| Boiling Point | 267.984ºC at 760 mmHg |
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| Molecular Formula | C5H7N3 |
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| Molecular Weight | 109.12900 |
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| Flash Point | 115.873ºC |
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| Exact Mass | 109.06400 |
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| PSA | 29.85000 |
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| LogP | 0.44660 |
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| Index of Refraction | 1.739 |
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| InChIKey | KPMVHELZNRNSMN-UHFFFAOYSA-N |
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| SMILES | c1cc2n(n1)CCN2 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- NJ5098950
- CHEMICAL NAME :
- 1H-Imidazo(1,2-b)pyrazole, 2,3-dihydro-
- CAS REGISTRY NUMBER :
- 6714-29-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C5-H7-N3
- MOLECULAR WEIGHT :
- 109.15
- WISWESSER LINE NOTATION :
- T55 ANN FM&TJ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 410 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 993 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) Behavioral - ataxia
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Behavioral - ataxia Gastrointestinal - nausea or vomiting
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 500 mg/kg/5D-I
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea Blood - normocytic anemia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 500 mg/kg/10D-I
- TOXIC EFFECTS :
- Blood - changes in erythrocyte (RBC) count
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 415 mg/kg/5D-I
- TOXIC EFFECTS :
- Liver - fatty liver degeneration Kidney, Ureter, Bladder - other changes Blood - hemorrhage
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Ascites tumor
- DOSE/DURATION :
- 600 mg/kg
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 20,2639,1971
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Safety Information
Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Imidazole-Pyrazole |
| 2,3-dihydro-1-H-imidazo<1,2,-6>pyrazole |
| IMPY |
| 2,2-b]pyrazole |
| imidazopyrazole |
